sirt1、acetyl-p53、c-myc在乳腺癌中的表达及其对预后的影响

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1、分类号：单位代码：10114密级：学号：201010002SIRT1、acetyl-P53、c-Myc在乳腺癌中的表达及其对预后的影响研究生：宋新峰指导教师：路喜安申请学位门类级别：医学硕士专业名称：病理学与病理生理学研究方向：肿瘤分子病理所在学院：基础医学院2013年6月1日学位论文独创性声明本人声明所呈交的学位论文系在导师路喜安教授指导下本人独立完成的研究成果。文中任何引用他人的成果，均已做出明确标注或得到许可。论文内容未包含法律意义上已属于他人的任何形式的研究成果，也不包含本人已用于其他学位申请的论文或成果。与我一同工作的同志对本研究所做的任何贡献

2、均已在论文中作了明确的说明并表示谢意。本文如违反上述声明，愿意承担以下责任和后果：1、交回学校授予的学位证书；2、学校可在相关媒体上对作者本人的行为进行通报；3、本文按照学校规定的方式，对因不当取得学位给学校造成的名誉损害，进行公开道歉。4、本人负责因论文成果不实产生的法律纠纷。论文作者签名：日期：年月日学位论文版权使用授权书本人完全了解山西医科大学有关保留、使用学位论文的规定，同意学校保留或向国家有关部门或机构送交论文的复印件和电子版，允许论文被查阅和借阅；本人授权山西医科大学可以将本学位论文的全部或部分内容编入有关数据库进行检索，可以采用影印、缩印或

3、其他复制手段保存论文和汇编本学位论文。本人离校后发表或使用学位论文或与该论文直接相关的学术论文或成果时，署名单位仍然为山西医科大学。(保密论文在解密后应遵守此规定)论文作者签名：日期：年月日指导教师签名：日期：年月日（本声明的版权归山西医科大学所有,未经许可,任何单位及任何个人不得擅自使用）山西医科大学硕士学位论文目录中文摘要·································································1英文摘要··············································

4、··················3缩略词表······························································6正文································································7前言··································································7材料与方法·····················································

5、········81．病例资料····························································82．SIRT1、acetyl-p53、c-Myc免疫组织化学染色·····························83．SIRT1、acetyl-p53、c-MycWesternblotting实验··························10实验结果······························································141．SIR

6、T1、cetyl-p53、c-Myc免疫组化染色·································142．SIRT1、acetyl-p53、c-MycWesternblotting结果··························15讨论··································································16结论··································································20参考文献········

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