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时间:2019-03-03
《2型糖尿病大血管并发症患者血浆脂联素质量浓度的变化》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、维普资讯http://www.cqvip.com中国实用内科杂志2005年10月第25卷第l0期·887·论著文章编号:1005—2194(2005)10—0887—032型糖尿病大血管并发症患者血浆脂联素质量浓度的变化韦秀英肖丽红【摘要】目的了解2型糖尿病大血管并发症患者血浆脂联素质量浓度的变化。方法2004—02~2005一O2对广西医科大学第五附属医院内分泌科住院的2型糖尿病并大血管病变组49例,2型糖尿病无大血管病变组54例,健康对照组35名,测定其血浆脂联素水平,同时测定糖尿病患者的血糖、血压、血脂、c肽水平.比较脂联素质量浓度的变化,分析其影响因素结果正常对照组、糖尿病无大血
2、管病变组、糖尿病有大血管病变组脂联素质量浓度依次降低,分别为(16.37±3.03)mg/L,(6.69±4、42)mg/L,(4.08±3.24)n1L.组间差异均有显著意义(P<0.001);其中糖尿病合并颈动脉增厚者血浆脂联素又明显低于糖尿病无颈动脉增厚者(P<0.01)。结论血浆脂联素质量浓度在2型糖尿病患者申明显降低,合并大血管病变者降得更低。提示在2型糖尿病合并大血管并发症患者的发病因素中,脂联素的降低有相当重要的关系【关键词】糖尿病大血管并发症脂联素中图分类号:R5文献标识码:AChangesofplasmaadiponectinconcentrationintype2di
3、abeticpatientswithmacrovascularcomplications.WeiXiuying,,XiaoLihong.EndocrinologyDepartment,thefifthAffiliatedHospitalofGuongxiMedicalLbdversity,Li.uzhou545001,ChinaAbstractObjectiveToinvestigatethechangesofplasmaadiponectinconcentrationintype2diabeticpatientswithmacrovascularcomplications.Method
4、sForty—ninecasesoftype2diabeticpatientswithmacrovascularcomplications,fifty—fourcasesoftype2diabeticpatientswithoutmacrovascularcomplicationsandthirty—fiveheahhypeoplewerein.vestigated.Theirplasmaadiponectinlevelswasassaved.Meanwhile,thelevelsofbloodpressure,plasmaglucose,.lipidsandC—peptidewerem
5、easured.Theplasmaadiponectinlevelsamongthreegroupswerecompared,aildthefac—totsaffectingtheplasmaadiponectlnwereanalyzed.ResultsTheplasmaadiponectinlmelsinthegroupoftype2dia—beteswithoutmacrovascularcomplicationswerelowerthaninthecontrolgroupandwerethelowestinthegroupoftype2diabeteswithmacrovascul
6、arcomplications.Theplasmaadiponectinlevelsofthesethreegroupswere(16.37±3.03)ms/L,(6.69±4.42)ms/L,(4.08-4-3.24)ms/L,respectively.Thedifferencesamongthethreegroupsweresta.tisticallysignificant(P7、pe2diabeticpatientswithoutincreasedcarotidIMT(P<0.001).ConclusionThelevelsofplasmaadiponectinintype2diabeticpatientissignificantlydecreased,andevenmoreintype2diabeticpatientwithmacrovascularcomplications.Theresultssugg
7、pe2diabeticpatientswithoutincreasedcarotidIMT(P<0.001).ConclusionThelevelsofplasmaadiponectinintype2diabeticpatientissignificantlydecreased,andevenmoreintype2diabeticpatientwithmacrovascularcomplications.Theresultssugg
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