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时间:2019-03-03
《前列地尔配合早期高压氧治疗突发性耳聋》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据·314·监鏖迟趁退渔垫!Q生生旦筮2≥鲞箜垒翅g!型!坐些趟璺趣塑鱼鱼丛迪h塑耻,y丛:垫:盟!:垒:△巳巫!垫!QIIZ前列地尔配合早期高压氧治疗突发性耳聋于建敏,孙玉蕊,张延平,张树新,何云,耿纪录[摘要】目的观察前列地尔配合早期高压氧治疗突发性耳聋的临床效果。方法选取发病l周内的突发性耳聋96例,随机分为治疗组(49例)和对照组(47例)。治疗组采用前列地尔注射液10¨g加0.9%氯化钠注射液静脉滴注,每天1次,同时配合高压氧治疗;对照组采用葛根素注射液500mg静脉滴注,每天1次,2周为1个疗程。治疗后比较两组纯音测听、耳
2、鸣、眩晕的改善情况。结果两组治疗后纯音测昕均有明显提高,与治疗前比较差异均有统计学意义(P<0.05);治疗组耳聋、耳呜和眩晕治疗的有效率分别为89.8%、89.3%、93.8%,对照组分别为76.6%、76.9%、78.6%,两组比较差异有统计学意义(P<0.05)。结论前列地尔配合早期高压氧治疗突发性耳聋、耳鸣效果理想。[关键词】前列地尔;高压氧;听力受损者[中国图书资料分类号】R764.437[文献标志码]A[文章编号】1002-3429(2010)04-0314-03ClinicalInvestigationonEffectsofL
3、ipo-ProstaglandinElCombinedwithHyperbaricOxygenTherapyin96Pa-tientswithSuddenDearnessandTinnitusYUJian·rain,SUNYu-rui,ZHANGYan·ping,ZHANGShu—xin,HEYun,GENGJi·h(Out·Patient·Department,the309”HospitalofPLA,Beijing100091,China)[Abstract]ObjectiveToobservetheclinicaleffectsofl
4、ipo—prostaglandinElwithearlyhyperbaricoxygenther-apyinpatientswithsuddendeafnessandtinnitus.Methods96patientswithsuddendeafnessweredividedintotreat·mentgroup(n=49)andcontrolgroup(n=47)randomly.PatientsintreatmentgroupweregivenAlprostadilInjection(10肛g)plussodiumchlorideinj
5、ection(0.9%)combinedwithhyperbaricoxygentherapy,whilepatientsincontrolgroupweregivenpuerarininjection(500mgivgtt),2weeksasacourseonly.Aftertreatment。puretoneaudiometrytestandeffectsoftinnitusanddizzinessimprovementwereevaluatedinthetwogroups.ResultsAftertreatment,hearingim
6、pairmentinthetwogroupsimprovedsignificantlycomparedwiththatbeforetreatment(P<0.05).Theeffectiveratesofhearinglossimprovement,tinnitusimprovementanddizzinessimprovementintreatmentgroupwere89.8%,89.3%and93.8%,respectively,significantlyhigherthanthatofcontrolgroup(76.6%,76.9%
7、,78.6%,P<0.05).Con·clusionLipo-prostaglandinE1combinedwithearlyhyperbaricoxygentherapyshouldbeanidealchoiceforpatientswithsuddendeafnessandtinnitus.[Keywords]Alprostadil;Hypebaricoxygenation;Hearingimpairedperson突发性耳聋、耳鸣以中老年居多,尤其伴有高血压、血脂紊乱、糖尿病、动脉粥样硬化等基础疾病的患者更易罹患一。1。目前该病主要采
8、取扩张血管、活血化瘀、营养神经等综合治疗。近年来前列地尔注射液(凯时)配合早期高压氧治疗突发性耳聋的效果受到越来越多的关注”’。为进一步探讨前列地尔配合早期高压氧治疗突发性耳聋、
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