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1、23.1%(3/13),二者均高于非血栓组，有明显统计学意义（P均<0.05）。CHA2DS2-VASc评分标准中其他因子在血栓组和非血栓组中差异均无统计学意义（P均>0.05）。CHA2DS2-VASc评分与LAD有统计学意义（P<0.05），且LAD在血栓组中高于非血栓组（P<0.05）。4.结论：随着CHA2DS2-VASc评分增高，NVAF患者LA/LAA血栓患病率成增高趋势。CHA2DS2-VASc评分=0时亦需行TEE或CTA以排除LA/LAA血栓形成。在本组研究中，CHA2DS2-VASc评分因子中，高血压病、心衰是增加LA/LAA血栓形成的重要的危险因素。左房扩
2、大对NVAF患者LA/LAA血栓形成也有预测意义。关键词：非瓣膜性心房颤动、CHA2DS2-VASc评分、左房/左心耳、血栓、心力衰竭3万方数据AbstractObjective:ThisstudyaimstoanalyzethepredictionofCHA2DS2-VAScscoresileftatrial/leftappendage(LA/LAA)thrombusformationofnonvalvularatrialfibrillationandinvestigatetherelationsofeachfactorofCHA2DS2-VAScscoresinpredic
3、tingLA/LAAthrombusformationofnonvalvularatrialfibrillation.Methods:AlldataswerecollectedfromthepatientswhohadnonvalvularatrialfibrillationpatientsandplanedtoundergoradiofrequencyablationorelectricalcardioversionincardiovascularmedicineofFujianProvincialHospitalbetweenJanuary2012andDecember20
4、13,includingCHA2DS2-VAScScores(Heartfailure,hypertension,age≥75years,diabetes,stroke/TIA,vasculardiseases,agefrom65to74yearsold,sex),Echocardiography(leftatrialdiameter),electrocardiographyorHolter,chestX-ray,transesophagealechocardiography(TEE),computedtomographyAngiography(CTA).Patientswer
5、edividedintothromboticgroupandnon-thromboticgroupaccordingtoTEEandCTA.WeanalyzedtherelationshipbetweenCHA2DS2-VAScscoresandLA/LAAthrombusformationusinglinearChi-square2testandusedX–testorFisherexacttesttoevaluatethefrequencydifferencesofeachfactorofCHA2DS2-VAScscoresinthetwogroups.Analysisof
6、variancewasappliedtoappraisedtherelationshipofCHA2DS2-VAScscoresandleftatrialdiameterandt-testwasusedtoanalyzedthedifferenceinthetwogroups.ThedifferencedetectingLA/LAA2thrombusformationbetweenTEEandCTAwasevaluatedbyX–test(McNemarmethod).Atlast,wecalculatedthesensitivity,specificity,thepositi
7、vepredictivevalueandthenegativepredictivevaluebasedonthegoldstandardusingTEE.4万方数据Results:Amongthetwohundredandthirty-threepatientsofnonvalvularatrialfibrillationwhowastoacceptpre-cardioversion,thirteenpatientswerediagnoisisedwithLA/LAAthrombusform
