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1、提要目的:本课题主要研究自拟疏肝消疣汤治疗疣状胃炎(中医辨证肝胃不和型)的临床疗效,并从理论和临床研究两个方面探讨自拟疏肝消疣汤治疗VG的机制,为其临床推广应用打下基础。方法:临床选择符合纳入标准的疣状胃炎患者60例,随机分成两组。试验组30例,给予中药汤剂(自拟疏肝消疣汤)治疗,水煎至300ml,早晚各温服150ml,日一剂;对照组30例,给予气滞胃痛颗粒治疗,每天3次,每次5g。治疗期间均不用其他治疗胃病药物。观察两组患者治疗前后的症状疗效,胃镜下胃粘膜改变和HP清除情况。结果:临床研究显示,试验
2、组和对照组的中医证候总有效率分别为90.00%和73.33%,胃镜疗效总有效率分别为83.33%和66.67%,HP清除率分别为61.54%和28.00%,两组疗效对比均有显著性差异(P<0.05)。试验组能明显改善患者胃脘疼痛,痛连两胁、胃脘胀满、吞酸嘈杂、嗳气等症状,其疗效优于对照组。结论:自拟疏肝消疣汤治疗疣状胃炎中医辩证肝胃不和型,能明显改善患者临床症状,胃镜下胃粘膜改变疗效显著且能有效清除HP,无明显不良反应及毒副作用,临床疗效确切。关键词疣状胃炎;自拟疏肝消疣汤;肝胃不和型;临床研究Cli
3、nicalStudyofTreatingVerrucosaGastritisofDisharmonyBetweenLiver-stmomachWithZi-ni-shu-gan-xiao-you-tangSpeciality:InternalMedicineofTCMAuthor:YuYaqunTutor:Prof.WangWeimingAbstractObjective:TostudythistopicistheShuGanawaywartsdecoction"inthetreatmentofliv
4、erstomachtypeverrucousgastritiswiththeclinicalcurativeeffect.Methods:Cross-sectionalsurvey,epidemiologysceneinvestigationmethods,to60casesverrucousgastritisintotwogroupsatrandom.30patientsinthetrial,giveChinesemedicineone(fromShuGanawaytowartssoup)treat
5、ment,waterfryingto300ml,temperatureinthemorningandtake150ml,dayoneagent;30casesin,giveprilosecmagnesiumenteric-coatedmetforminhydrochloridetreatmenttwiceaday,everyday,everytime20mg.Duringtreatmentarenototherdrugsforstomach.Observebothgroupsofpatientsbef
6、oreandaftertreatmentefficacyofsymptoms,pulsechangeunderthetongueandgastroscopegastricmucosachange.Results:Clinicalstudiesshowthat,thetreatmentgroupandcontrolgroupsymptomsoftraditionalChinesemedicalsyndromeeffectiveratewas90.00%and73.33%,withthetotaleffe
7、ctiverateofcurativeeffectto83.33%and66.67%,respectively,HPclearancerateswere61.54%and28.00%,twogroupsofcurativeeffectaresignificantdifferencecompared(P<0.05).Thetreatmentgroupcansignificantlyimprovepatientswithapproachthepain,thepainevenapproachthefullb
8、ilge,twothreat,swallowedacidnoisy,belchsymptoms,itscurativeeffectisbetterthanthecontrolgroup.Conclusion:TheZi-ni-shu-gan-xiao-you-tangtotreatmentverrucousgastritiswithtraditionalChinesemedicinedialecticalliverstomachtype,cansigni