食管癌原发灶pet2fct+fdg摄取与临床病理参数与预后的关系分析

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1、食管癌原发灶PET／CTFDG摄取与临床病理参数及预后的关系研究TheStudyonClinicalPath0109icalFactorsandPrognosisImpacting18一F1uorodeoxy91ucoseUptakeofn●m’n1，、‘rrlmary1umor1nESOpnagea上乙arc1nomaPostgraduateMajorTutorFenRuiengRuiOncologyYuJinmingProfessorAbstractPartOne：TheStudyonClinicalPathologicalFactorsImp

2、actingFDGUptakeofPrimaryTumorinEsophagealCarcinomaObjective：Fluorodeoxyglucose—PETisbecomingthestandardofcareininitialstaging，monitoringtheresponsetotherapyanddetectionofrecurrentesophagealcarcinoma．However，theclinicalandpathologicalfactorssuchasage，gender，thelength，thedepth，t

3、hepathologicaldifferentiationandlymphnodestatusinrelationtothiSimportantmeasurementhavenotbeenreportedpreviously．Methods：FromJune2004toNovember2006，68operablepatientswithesophagealcarcinomawereenrolledinthisstudy．Allofthemhadwholebody18F—fluorodeoxy91ucosePET／CTscannedbeforeth

4、eoperation．Thelengthanddepthofinvasion，pathologicaldifferentiationoftheprimarylesions，andlymphnodemetastasisstatus．weredeterminedbypostoperativepathology．Tumoruptakewasquantitatedbymaximumstandardizeduptakevalue(SUVmax)．Results：FortheFDGuptakevaluesintheprimarylesion，therewasa

5、significantstatisticaldifferenceindifferentlengthgroups，butnotingroupsofdifferentgendersandages．Therewasalsoasignificantstatisticaldifferencebetweenlowdifferentiation，intermiddle5山东省医学科学院硕士学位论文differentiationandhighdifferentiationgroups(r=O．781，P=O．000)．Positivecorrelationwasn

6、oticedbetweentheSUV—andthedepth(r=O．860，P=O．000)．Furthermore，statisticalanalysisshowedthedifferenceinSUv眦betweennolymphnodemetastasisgroupandlymphnodemetastasisgroup(r=O．852，P=O．000)．Conclusion：Theprimarylesionlength，depthandpathologicaldifferentiation，butnottheageandgender，ar

7、erelatedtotheFDGuptakeinpatientswithesophagealcarcinoma．Increasedmaximumstandardizeduptakevalueintheprimarylesionmaypredictlymphnodemetastasisatpresentationorlaterstageinesophagealcarcinoma．PartTwo：TheRelationshipbetweenPET／CTFDGUptakeofEsophagealCarcinomaPrimaryLesionsandProg

8、nosisObjective：ToinvestigatetherelationshipbetweenFDGuptakeof