先天性心脏病(chd)与环境因素的关系分析

先天性心脏病(chd)与环境因素的关系分析

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时间:2019-02-28

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1、浙江大学硕士学位论文英文摘要StudyonrelationshipbetweenenvironmentalfactorsandcongenitalheartdiseaseZhejiangUniversitySchoolofMedicinePediatryMasterDegreeGraduateLeiZhaoSuperbisorGuo-PingJiangAbstraetobjective:Congenitalheartdisease(CHDlisthemostcommoncongenitalmalformationsinthenewbo

2、rns.CHDhasbecomethemaincauseofdeathinthechildrenlessthan5years.Weinvestigatedthe1000casesofCHDtOdetermineenvironmentalriskfactorsinthedevelopmentofCHD.AndwewilldiscusstherelationshipbetweentheseasondistributionofCHDandseasonalvariationofairpollution.CHDandthelivingenvir

3、onmentintheearlystageofpregnancy,CHDandtheteratogenicsubstancescontacfionintheearlystageofpregnancy,CHDandfolicacid,CHDandtheadvancedagepregnantwoman.PrimarypreventionmeasureswillbeofferedforCHD.Methods:Reviewedthe1000caseswerediagnosedbyechocardiographyinOUrhospitalfro

4、mMay2010toMay2012.Male:547cases,female:453cases,aged:1dayto6.5years(average:0.8years).Echocardiographywasperformedbyphysiciansandfollowingtheunifiedprotocolsanddiagnosisstandards.Face-to—facestructuredinterviewwerecarriedouttotheCHDpatients’mothers.DatawerecollectedandI

5、VgraphsweremadebyEXCELsoftware.StatisticalanalysisWaSmadebySTATA12·0·UsedLogisticmodeltocontrolconfoundingandanalyzetheinfluencingfactors.Results:1.ThepeakofUrbanairpollutionisshowedintheseasonreplacementperiod.TheincidenceofCHDhasthesimilarseasonalvariationwithairpollu

6、tion.2.TheriskofthehJlghincidenceofCHDareassociatedwithmanyenvironmentalfactorsduringpregnancy,suchaslivingcondition,influenza,X—ray,,depressedcondition,exposuretoorganicsolventsorchemicalrawmaterialsinearlystageofpregnancy,mother’Seducation,threatenedabortion,excessive

7、smokingoffather.3.ThreatenedabortionandexposuretoorganicsolventsinearlystageofpregnancyincreasetheriskofCyanoticCHDConelusions:1.TheriskofthehighincidenceofCyanoticCHDareassociatedwithmanyenvironmentalfactorsduringpregnancy,suchasinfluenza,X—ray,exposuretosolventsinearl

8、ystageofpregnancy,mother’Seducation,threatenedabortion,excessivesmokingoffather.2.TheriskofthehighincidenceofN

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