胺碘酮治疗老年人心律失常疗效观察

《胺碘酮治疗老年人心律失常疗效观察》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、山东大学硕士学位论文THEEFFECToFAMIoDARoNEoNTHESENILEP枷ENTSSUFFERINGFRoMARRHYTHMIAPostgraduateLijuanSunTutorJianchunWangABSTRACTBackgroundWi也theagingofhumanbody,thecardiovascularsystemalsochangesinstrcutureandphysiologicalfunction，whichleadstOtheappearanceofarrhythmiacharacterizedbydecreasedp

2、aceaction，conductivedysfunctionandectopicactivation．Andthehepaticandrenalfunctionoftheseniledecrease，thehalflifeofmedicineisprolonged,whichaffectsthesenile’sendurance．SoitisofgreatsignificancetOsearchsafeandeffectiveantiarrhythmicagentsfortheincidenceandmortalitydecreaseofsenilearr

3、hythmia．AmiodaronehasbeengenerallyclassifiedasaVaul曲all—WilliamsclassIIIagent，italsohasclassI，classIIandclassIVactivity．Itcanbeusedtomanagevirtuallyallformsofsupraventricularandventriculartachycadia诵tIIclinicalsignificance，itbecomesthefocusofstudiespublished，andalsothemost-often-pr

4、escribedantiarrythmicagent．Buttherearefewstudiesaboutitsclinicaleffectandsafetyontheelderlypopulation．objeetive1．Toexploretheefficacyofamiodaroneonthesenilepatientssufferingfromfrequentprematureventricularcontractionsandatrialfibrillation；2．ToexploretheadverseeffectsofamiodaroneOnc

5、ardiovascularsystemandextra-cardiovascularsystemwhenusedinsenilepatients．Materialandmethods1．patient：Weselected88patients(age>／60y)，amongthemtherewere24patientswithfrequentprematureventricularcontractions(PVCs，meanPVCs>30beats／hour)，30patientswithparoxysmalatrialfibrillation(AF)and

6、34patientswithpersistentAF．WedividedthepatientswithfrequentPVCsand4山东大学硕士学位论文persistentAFintoAmgroup(8c￡kqeswithPVCs，13caseswithAF)、Prgroup(8easeswithPVCs，11caseswithADandMogroup($casesmmPVCs，10caseswithAF)，andpatientswithparoxysmalAFintoAmgroup(15cases)andPrgroup(15cases)．Atthesam

7、etimeweselected34patientsyoungerthan60y(Younggroup)，amongthemtherewgqt'e12patientswithfrequentPVCs，12patientswithparoxysmalAFand10patientswithpersistentAF,andallofthemweretreatedwithamiodarone．2．Treatmentmethod：Allofthepatientsbegantoaccepttreatmentafterstoppingotherantiarrhythmiad

8、rugsfur5half-livesandsyste