欢迎来到天天文库
浏览记录
ID:33403742
大小:938.29 KB
页数:32页
时间:2019-02-25
《中性粒细胞与淋巴细胞比值在鼻咽癌的临床意义初探》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、重庆医科大学硕士学位论文中性粒细胞与淋巴细胞比值在鼻咽癌的临床意义初探姓名:叶枝依申请学位级别:硕士专业:耳鼻咽喉科学指导教师:骆文龙201205重庆医科大学硕士研究生学位论文中性粒细胞与淋巴细胞比值在鼻咽癌的临床意义初探摘要目的:在大多数恶性肿瘤当中,升高的中性粒细胞/淋巴细胞比值(Neu扛ophil-to-LymphocyteRatio,NLR)提示肿瘤的不良预后,研究显示,高中性粒细胞/淋巴细胞比值与胃癌、肝癌、肺癌、结肠癌、胰腺癌等肿瘤患者的死亡率密切相关。然而,中性粒细胞/淋巴细胞比值与鼻咽癌预后的关系仍然不是十分清楚,就此
2、本文对中性粒细胞/淋巴细胞比值在鼻咽癌预后的临床意义进行探讨。方法:回顾性分析2001年1月至20lO年1月我院116例鼻咽癌患者(男76例,女40例),记录年龄、性别、白细胞计数(、阳C)、中性粒细胞计数(N)、淋巴细胞计数(L),并计算出中性粒细膨淋巴细胞比值(NLR),比较116例患者中复发与未复发者年龄、性别、中性粒细胞计数(N)、淋巴细胞计数(L),NLR,分析比较年龄、性别、N、L、NIU对鼻咽癌患者预后的影响。结果:复发组NLR明显高于未复发组(尸3、Ik3.69时,其中未复发与复发比例:79.41%,20.59%,NLR≥3.69时,未复发与复发比例:20.83%,79.17%。差异具有统计学意义(尸4、LIN【CALvAI^mOFNEUTRO咖L.TO.IYM吧HoCYTERATIoINNASoPHARYNGEALCARC矾O№ko啊ec戗'忱:Ani11creaseinmeneutropllil·to—lymphocyteratio(NLR)isassociatedwithpoorpro印osisf.orVariouscallcers,andmeelevatedneu仃opllil-to-1ymphoc”eratio(NLR)isastrongpredictorofmortali哆iIlpatientswithgastriccaI5、lcer’h印atocellularcancer,lungcancer,c010rectalcallcer,paJlcreaticcancerandetc..HoweVer'theclinicalimplicationofthechangeinmeneu仃opllil-to-lymphocyteratioinpadentswitllnasopha巧ngealcarcinomaremainslmknown.Therefore,meaimofthestudyistoexploremecliIlicalValueofneu仃opml-to-6、lyIIlphocyteratio(NLR)innasopha巧ngealc2urcilloma(NPC)patients.M岫OdS:0neh眦dredandsiXteencasesofcon6mledNPC行omJaJluary2001toJallua巧2010werereViewedretrospectiVely(male76cases,female40cases).Theage,gender,whitebloodcell(WBC)counts,neu仃opllilcounts(N),lymphocytecounts(L)ofa7、llthepatientswererecordedrespectiVely,andneutroph订-to—lymphocyteratiowerecalculatedthen.T11eage,gender,neutrophilcounts,1ymphocytecountsaJldneu仃opllil-to—lymphocyteratiowerecompauredamongthepatientswi血4重庆医科大学硕士研究生学位论文rec硼renceandnon—recurrence,aIldanalysedwhemerthefacto8、rsarepredictiVeofrecurrenceinnasopha巧ngealcarcilloma.R鹤ul伍:7Ihe1eVelofNLRinrecurrent缪oupwereobViouslyK曲erthaJl
3、Ik3.69时,其中未复发与复发比例:79.41%,20.59%,NLR≥3.69时,未复发与复发比例:20.83%,79.17%。差异具有统计学意义(尸4、LIN【CALvAI^mOFNEUTRO咖L.TO.IYM吧HoCYTERATIoINNASoPHARYNGEALCARC矾O№ko啊ec戗'忱:Ani11creaseinmeneutropllil·to—lymphocyteratio(NLR)isassociatedwithpoorpro印osisf.orVariouscallcers,andmeelevatedneu仃opllil-to-1ymphoc”eratio(NLR)isastrongpredictorofmortali哆iIlpatientswithgastriccaI5、lcer’h印atocellularcancer,lungcancer,c010rectalcallcer,paJlcreaticcancerandetc..HoweVer'theclinicalimplicationofthechangeinmeneu仃opllil-to-lymphocyteratioinpadentswitllnasopha巧ngealcarcinomaremainslmknown.Therefore,meaimofthestudyistoexploremecliIlicalValueofneu仃opml-to-6、lyIIlphocyteratio(NLR)innasopha巧ngealc2urcilloma(NPC)patients.M岫OdS:0neh眦dredandsiXteencasesofcon6mledNPC行omJaJluary2001toJallua巧2010werereViewedretrospectiVely(male76cases,female40cases).Theage,gender,whitebloodcell(WBC)counts,neu仃opllilcounts(N),lymphocytecounts(L)ofa7、llthepatientswererecordedrespectiVely,andneutroph订-to—lymphocyteratiowerecalculatedthen.T11eage,gender,neutrophilcounts,1ymphocytecountsaJldneu仃opllil-to—lymphocyteratiowerecompauredamongthepatientswi血4重庆医科大学硕士研究生学位论文rec硼renceandnon—recurrence,aIldanalysedwhemerthefacto8、rsarepredictiVeofrecurrenceinnasopha巧ngealcarcilloma.R鹤ul伍:7Ihe1eVelofNLRinrecurrent缪oupwereobViouslyK曲erthaJl
4、LIN【CALvAI^mOFNEUTRO咖L.TO.IYM吧HoCYTERATIoINNASoPHARYNGEALCARC矾O№ko啊ec戗'忱:Ani11creaseinmeneutropllil·to—lymphocyteratio(NLR)isassociatedwithpoorpro印osisf.orVariouscallcers,andmeelevatedneu仃opllil-to-1ymphoc”eratio(NLR)isastrongpredictorofmortali哆iIlpatientswithgastriccaI
5、lcer’h印atocellularcancer,lungcancer,c010rectalcallcer,paJlcreaticcancerandetc..HoweVer'theclinicalimplicationofthechangeinmeneu仃opllil-to-lymphocyteratioinpadentswitllnasopha巧ngealcarcinomaremainslmknown.Therefore,meaimofthestudyistoexploremecliIlicalValueofneu仃opml-to-
6、lyIIlphocyteratio(NLR)innasopha巧ngealc2urcilloma(NPC)patients.M岫OdS:0neh眦dredandsiXteencasesofcon6mledNPC行omJaJluary2001toJallua巧2010werereViewedretrospectiVely(male76cases,female40cases).Theage,gender,whitebloodcell(WBC)counts,neu仃opllilcounts(N),lymphocytecounts(L)ofa
7、llthepatientswererecordedrespectiVely,andneutroph订-to—lymphocyteratiowerecalculatedthen.T11eage,gender,neutrophilcounts,1ymphocytecountsaJldneu仃opllil-to—lymphocyteratiowerecompauredamongthepatientswi血4重庆医科大学硕士研究生学位论文rec硼renceandnon—recurrence,aIldanalysedwhemerthefacto
8、rsarepredictiVeofrecurrenceinnasopha巧ngealcarcilloma.R鹤ul伍:7Ihe1eVelofNLRinrecurrent缪oupwereobViouslyK曲erthaJl
此文档下载收益归作者所有