全基因组关联研究meta分析搜寻中国汉族人系统性红斑狼疮易感基因

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1、目录英文缩略词表...............................................................................................1中文摘要.......................................................................................................4ABSTRACT.......................................................

2、...........................................7正文.............................................................................................................111引言.......................................................................................................111.1研究背景...

3、......................................................................................111.2本课题的研究设计方案.................................................................162实验材料与方法...................................................................................182.1研究对象.......

4、..................................................................................182.2实验试剂.........................................................................................202.3实验仪器......................................................................................

5、...222.4分析软件和电子数据库查询信息.................................................252.5实验方法.........................................................................................292.6数据分析.........................................................................................593结果...

6、....................................................................................................673.1研究对象.........................................................................................673.2IMPUTATION结果............................................................

7、.................693.3META分析结果...............................................................................693.4验证阶段分型数据的统计分析结果.............................................703.5合并27个SNPS的META分析和验证阶段的统计分析结果.....853.6关联SNPS的遗传模式分析.............................................

8、.............853.7关联位点的基因型-表型分析............................................