全基因组关联研究meta的分析搜寻中国汉族人系统性红斑狼疮易感基因

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1、目录英文缩略词表...............................................................................................1中文摘要.......................................................................................................4ABSTRACT.................................................

2、.................................................7正文.............................................................................................................111引言.......................................................................................................

3、111.1研究背景.........................................................................................111.2本课题的研究设计方案.................................................................162实验材料与方法.................................................................................

4、..182.1研究对象.........................................................................................182.2实验试剂.........................................................................................202.3实验仪器..............................................................

5、...........................222.4分析软件和电子数据库查询信息.................................................252.5实验方法.........................................................................................292.6数据分析...................................................................

6、......................593结果.......................................................................................................673.1研究对象.........................................................................................673.2IMPUTATION结果........................

7、.....................................................693.3META分析结果...............................................................................693.4验证阶段分型数据的统计分析结果.............................................703.5合并27个SNPS的META分析和验证阶段的统计分析结果.....853.6关联SNPS的遗传模式分析...

8、.......................................................853.7关联位点的基因型-表型分析............................................