血清铁蛋白检测在乳腺癌新辅助化疗疗效评估与预后预测的价值

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1、万方数据血清铁蛋白检测在乳腺癌新辅助化疗疗效评估及预后预测的价值硕士毕业论文POTENTIALVALUESINRESPoNSEEVALUATIONANDASSESSINGPROGNOSISOFDETECTIONOFSERUMFERRITINFoRBREASTCANCERWITHNEoADJlnANTCHEMoTHERAPYABSTRACTObjectiveTodiscusstheclinicalvalueoftheserumferritinlevelsinpredictingchemotherapeuticrespons

2、eandprognosisfor150patientswithbreastcancertreatedbyneoadjuvantchemotherapy．Method(1)Todetecttheserumferritinlevelsof60patientswithbenignbreastdiseasespriotreatmentandthatof150patientswithbreastcancerbeforeneoadjuvantchemotherapy,beforeandafterchemotherapeuticeve

3、rycycle，preoperativeand21daysafteroperationbyusingradioimmunoassay；andtoevaluatetheeffectivenessbytheMRIafterevery2cyclesofneoadjuvantchemotherapyforthepaitientswithbreastcancer．(2)Todrawthescatterdiagram，andthenremovetheinfluentialobservationsandthehighleveragec

4、ases．Tocomparethelevelsoftheserumferritinbetweenthe60patientswithbenignbreastdiseasespriotreatmentand60patientswithbreastcancerbeforechemotherapybyrandomsampling，thentodeterminethebestvalueoftheserumferritinlevelbydrawingtheROCcurveforassistingthediagnosisofbreas

5、tcancer．(3)Todescribethemedianoftheserumferritinlevelsofpaitientswithbreastcancerinallstages，andtoexplainthecorrelationbetweentheserum3万方数据血清铁蛋白检测在乳腺癌新辅助化疗疗效评估及预后预测的价值硕士毕业论文ferritinlevelsafterneoadjuvantchemotherapyandtheclinicalresponsebylogisticanalysisofregres

6、sion，drawingtheROCcurveandtoensurethat(a)theoptimalvalueoftheserumferritintoevaluatetheeffectivenessofneoadjuvantchemotherapyforthepaitientswithbreastcancer；(b)Tomakesurethebestboundaryvalueeffectivelyofthechange(ASF1)oftheserumferritinlevelandthatoftheMRIimaging

7、evaluationafterevery2cyclesofneoadjuvantchemotherapyforthepaitientswithbreastcancer．(4)ToexplaintherelationshipbytheChi-squareanalysisbetweenthechange(ASF2)oftheserumferritinlevelsbeforeandafteroperationandtherecurrenceormetastasisofthepaitientswithbreastcanceraf

8、terresection．Thecomparisonofthemedianoftheserumferritinlevelsinothergroupsareanalysedbyrank．sumtest．Results(1)Therageoftheserumferritinlevels衍也thebreastcancerb