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ID:33397630
大小:1.36 MB
页数:29页
时间:2019-02-25
《血清铁蛋白检测在乳腺癌新辅助化疗疗效评估与预后预测的价值》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据血清铁蛋白检测在乳腺癌新辅助化疗疗效评估及预后预测的价值硕士毕业论文POTENTIALVALUESINRESPoNSEEVALUATIONANDASSESSINGPROGNOSISOFDETECTIONOFSERUMFERRITINFoRBREASTCANCERWITHNEoADJlnANTCHEMoTHERAPYABSTRACTObjectiveTodiscusstheclinicalvalueoftheserumferritinlevelsinpredictingchemotherapeuticrespons
2、eandprognosisfor150patientswithbreastcancertreatedbyneoadjuvantchemotherapy.Method(1)Todetecttheserumferritinlevelsof60patientswithbenignbreastdiseasespriotreatmentandthatof150patientswithbreastcancerbeforeneoadjuvantchemotherapy,beforeandafterchemotherapeuticeve
3、rycycle,preoperativeand21daysafteroperationbyusingradioimmunoassay;andtoevaluatetheeffectivenessbytheMRIafterevery2cyclesofneoadjuvantchemotherapyforthepaitientswithbreastcancer.(2)Todrawthescatterdiagram,andthenremovetheinfluentialobservationsandthehighleveragec
4、ases.Tocomparethelevelsoftheserumferritinbetweenthe60patientswithbenignbreastdiseasespriotreatmentand60patientswithbreastcancerbeforechemotherapybyrandomsampling,thentodeterminethebestvalueoftheserumferritinlevelbydrawingtheROCcurveforassistingthediagnosisofbreas
5、tcancer.(3)Todescribethemedianoftheserumferritinlevelsofpaitientswithbreastcancerinallstages,andtoexplainthecorrelationbetweentheserum3万方数据血清铁蛋白检测在乳腺癌新辅助化疗疗效评估及预后预测的价值硕士毕业论文ferritinlevelsafterneoadjuvantchemotherapyandtheclinicalresponsebylogisticanalysisofregres
6、sion,drawingtheROCcurveandtoensurethat(a)theoptimalvalueoftheserumferritintoevaluatetheeffectivenessofneoadjuvantchemotherapyforthepaitientswithbreastcancer;(b)Tomakesurethebestboundaryvalueeffectivelyofthechange(ASF1)oftheserumferritinlevelandthatoftheMRIimaging
7、evaluationafterevery2cyclesofneoadjuvantchemotherapyforthepaitientswithbreastcancer.(4)ToexplaintherelationshipbytheChi-squareanalysisbetweenthechange(ASF2)oftheserumferritinlevelsbeforeandafteroperationandtherecurrenceormetastasisofthepaitientswithbreastcanceraf
8、terresection.Thecomparisonofthemedianoftheserumferritinlevelsinothergroupsareanalysedbyrank.sumtest.Results(1)Therageoftheserumferritinlevels衍也thebreastcancerb
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