失神经对幼兔干骺端损伤愈合影响的实验分析

《失神经对幼兔干骺端损伤愈合影响的实验分析》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、中文摘要周围神经系统对干骺端骨代谢及其成骨塑形作用具有调控作用，从而完成骨的正常生长发育和损伤修复过程。3、周围神经对骨折愈合的调控可能是通过分泌多种神经肽介导的。神经肽通过复杂的网络调节系统发挥其调控作用，但该网络系统中各因素之间的协调／拮抗作用尚待进一步研究阐明。4、周围神经系统可促进骨折部位钙、磷的沉积，促进类骨质矿化，促进骨痂成熟，使骨小梁正常重建，并顺力线排列。5、干骺端骨折合并周围神经损伤者应及早处理，以免延误病情造成神经进一步损伤，并影响骨折愈合质量。关键词：干骺端；失神经；神经肽；骨密度；组织学英文摘要Experiment

2、alStudyonTibialMetaphysealFractureRepairingandRemodelingafterSciaticNerveandFemoralNerveSectioninimmaturerabbitsABSTRACTObjective：1hebonefracturecicatrizationisaverycomplexwoundrepairprocess，withtheinfluencesandregulationofmanyfactors，inwhichnervoussystem。Scontrolactionho

3、ldsaveryimportantstatus．Studiesfoundthatnervefibersplayedaregulatoryrolebythereleaseofavarietyofneurotransmitters，butthespecificadjustmentmechanismisnotentirelyclear．Itisfrequenttoseechildrenwithmetaphysealfracturescomplicatingwithperipheralnerveinjuryinclinic，buttheinflu

4、enceofperipheralnerveonmetaphysealfracturehealinganditscontrolmechanismneedstobefurtherstudied．Inthisexperimentmodelsoftibialmetaphysealbonedefectwithdenervationweremade，andthedifferencesinhealingofmetaphysisbetweentheexperimentgroupandcontrolgroupwerecomparedwithafterava

5、rietyofphysicalexaminationandobservationundermicroscope．ThentheeffectofperipheralmjurythehealingoftibialOtpenplaeralnerveuryonehealingoftibialmetaoh。‘vsi‘‘sanditspossibleregulatorymechanismwereexplored，SOtOprovidesometheoreticalbasisforpromotingchildren'smetaphysealfractu

6、rehealingbyimprovingneurologicalfunction．英文摘要Methods：40healthyNewZealandyoungrabbitswhoseageswere4-6weeks，andbodyweightswere1．0一l。5kgwereselected．Undertheasepticcondition，verticalcutWasmarkedinfrontofthelefthindlegskneejointatthelevelofshinbonetubercle．Themetaphysicofshin

7、bonenear-endandtheepiphysealplatethatwaslikewhitethinlinewereexposedfully．Powerdrillwhosediameterwas3ramwasusedtodrillholeinepiphysealplateparalleldirectionintheposition0．5cmunderepiphysealplatefromshinboneinnerside，tomakeabonedefectlcmlongapproximately．Whatshouldbepaidat

8、tentiontowasthatdon’tinjurytheepiphysealplateandthearticularcartilage．Becausethetibialmetaphysea