周围神经损伤对骺板发育影响的实验分析

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1、英文摘要—————————————————————————————————————-一一_TheEffectsofPeripheralNerveInjuriesOnEpiphysealPlateDevelopmentABSTRACTObjective：Thefunctionofthevertebrateskeletond．eterminstheskeletalshapeandsize，buttheydevelopwithgrowthpatternwhichisenchondralboneformation．Theepiphysealplatebetweenos

2、teoepiphysisandmetaphysisofthelongboneunceasinglyproliferatesandthickens．t11einterstitialsubstancecalcifies，andthecartilagecellgeneratesapoptosis，finallynewlyformedbonedeposites，whichformslongitudinalgrowthofthediaphysis．Thephysiologicalactivityandbiologicalbehaviouroftheepiphysealp

3、lateiscomplicated，whichisaffectedbymanyfactors．Recentlyalthoughnumerousscholarsgainsomeachievementinthedirectepiphysealplateinjuryandmicroelementdeficiencywhichaffecttheepiphysealplatedevelopment；theresearchthattheperipheralnerveinjuryinfluencestheepiphysealplatedevelopmentisldom．Th

4、"：chintendstabammalmodel—fseldomhisresearchintendstoestablishtheanimalmodelof●thesciaticnerveandfemoralnerveinjuries，andobservethedevelopmentalcapacityoftheepiphysealplatethroughthemethodsofphysicalexamination，imageologyandmicroscope，inordertodiscussthefunctionandmechanismofperipher

5、alnerveinjuriesonepiphysealplatedevelopment，thusprovidethetheoreticalbasisforthemorereasonableandeffectiveclinic英文摘要treatmenttotheperipheralnerveinjuryoftheyoungchildrenandteenager．Methods：Select40healthyrabbitsaged6-8weeks，bodyweight1．0～1．4kg，maleorfemale，andintroducehomobodyrefere

6、ncemethod．Cutthesciaticnerveandfemoralnerveoftheleftlegabout1cmastheexperimentalgroupandtherightlegisn’tcutasthecomparisongroup．Afterbeinganesthetizedbyintramuscularinjectionofketamine(20mg／kg)，applyadeclinedcutabout2．5cmlongundertheleft-sidefundament，exposeandidentifythesciaticnerv

7、e，andcutitsdistalsegmentaboutlcm。attheinferiormarginofthepiriformmuscleabout0．5cm．Thesamemethodistoapplyacutabout2．0cmlongundertheleft．sideinguinalgroove，exposeandidentifythefemoralnervewhichlocatesthefemoralarterylaterally,andcutitsdistalsegmentabout1cmattheinferiormarginofthecrura

8、lligamentabout0．5cm