sp对幼兔干骺端损伤愈合影响的实验分析

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1、英文摘要ExperimentalStudyonSPinTibialMetaphysealFractureRepairingandRemodelingafterSciaticNerveandFemoralNerveSectioninimmaturerabbitsABSTRACTobjective：ThebonefracturecicatrizationiSaverycomplexwoundrepairprocess，withtheinfluencesandregulationofmanyfactor

2、s，inwhichnervoussystem’Scontrolactionholdsaveryimportantstatus．Studiesfoundthatnervefibersplayedaregulatoryrolebythereleaseofavarietyofneurotransmitters，butthespecificadjustmentmechanism1Snotentirelyclear．ItiSfrequenttoseechildrenwithmetaphysealfractu

3、rescomplicatingwithperipheralnerveinjuryinclinic，buttheinfluenceofperipheralnerveonmetaphysealfracturehealinganditscontrolmechanismneedstobefurtherstudied．Inthisexperimentmodelsoftibialmetaphysealbonedefectwithdenervationweremade，andthedifferencesinhe

4、alingofmetaphysisbetweentheexperimentgroupandcontrolgroupwerecomparedwithafteravarietyofphysicalexaminationandobservationundermicroscope．Thentheeffectofneuropeptideonthehealingoftibialmetaphysisanditspossibleregulatorymechanismwereexplored，SOtOprovide

5、sometheoreticalbasisforpromotingchildren’Smetaphysealfracturehealingbyimprovingneurologicalfunction．英文摘要Methods：40healthychinawhiterabbitswhoseageswere4—6weeks，andbodyweightswere1．0—1．5kgwereselected．Undertheasepticcondition，verticalcutwasmarkedinfron

6、tofthelefthindlegskneejointatthelevelofshinbonetubercle．Themetaphysicofshinbonenear-endandtheepiphysealplatethatwaslikewhitethinlinewereexposedfully．Powerdrillwhosediameterwas3mmwasusedtodrillholeinepiphysealplateparalleldirectionintheposition0．5cmund

7、erepiphysealplatefromshinboneinnerside，tomakeabonedefectlcmlongapproximately．Whatshouldbepaidattentiontowasthatdon’tinjurytheepiphysealplateandthearticularcartilage．Becausethetibialmetaphysealdamageofbonedefecttypewasstable，itwasnotnecessarytofixthein

8、juredlegsinsideandoutside．Alltheyoungrabbitswererandomlydividedintotwogroups：thetibialmetaphysealdamagegroupwithoutinnervation(experimentalgroup)andthatwithinnervation(controlgroup)．Thesciaticnerveandfemoralnerveoftheleftsideofhindlegsofyoungr