3.0t磁敏感加权成像、弥散加权成像与弥散张量成像对兔颅脑爆震伤的实验分析

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1、英文摘要EXPERIMENTALSTUDYOF3．0TSUSCEPTIBILITYWEIGHTEDIMAGING，DIFFUSIONWEIGHTEDIMAGINGANDDIFFUSIONTENSORIMAGINGINTHECEREBRALBLASTINJURYOFTHERABBITSABSTRACTCerebralblastinjuryprimarilymanifestsashemorrhagicfoci，non—hemorrhagicfociandwhitematterfiberinjury，butCT

2、androutineMRIcannotfindprophasediseaseeasily，howeversusceptibilityweightedimaging，diffusionweightedimaginganddiffusiontensorimagingcanshowedthediseaseearly．Soitisimportanttoinvestigatethevalueofsusceptibilityweightedimaging(swo，diffusionweightedimaging(DⅥ

3、)anddiffusiontensorimaging(DTI)indiagnosisofhemorrhagicloci，non—hemorrhagicfoci，andwhitematterfiberinjuryearlyafterblastinginrabbits，Italsostudiesthehemorrhagicfoci，andnon—hemorrhagicfoci．Atthesametime，therelationshipofADCvalue，FA-。valueandit’Slivingtimea

4、lsoresearched．Diffusiontensortrackingshowedtheinjurycategoriesofwhitematterfiberinjuryafteritsblasting，Itprovidesareferringbasisintheearlydiagnosis，treatmentandforecastprognosisofcerebralinjury．ThirtyNewZealandrabbitswereselected，andmodelofcerebralblastin

5、jurywasestablished．CT，routinemagneticresonanceimaging(MRI)，SWI，DWIandDTlwereperformedaftertheirinjury，andvariousanalysesofregionofinterestwereconductedwithmultiplanarpostprocessingtechnologyFunctool2Software．Thecerebralhistopathologicalchangeswereobserved

6、，andcontrastanalyseswerecamedoutwithfindingsfromSWI，DWIandDTIofthesameplane．Position，number，form，ADCvalue，FAvalueandinjurycategoriesofwhitematterfiberinjurywererecorded．Thedatawasinputandanalyzed1英文摘要byusingSPSS17．0statisticalsoftware．Ofthe30rabbits，there

7、wereno一。b。‘ainafindinas‘6rabbitsbyCT，T1WIandT2WIabnormalcerebralimagingtmdmgsinoraODltSanu1，一，’onlygasesandanlargeareaofhemorrhagewereshowedinCT，andtherewasnOabnormalin2ofthe6rabbitsbySWI，DWl，DTI．In30rabbits，22，102，221，738hemorrhagicfocusesweredetectedbyt

8、hedifferencesofCT，T1WI，T2WI，SWI．ThenumberofcerebralmicrobleedsdetectedbySWlwassignificantlylargerthanthoserevealedbyconventionalT1WI，T2WI(贮=10．00，P<0．010)，SWIimagingshowspunctiform(315／42．7％)，lamellar(218／29．5％)，sli