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ID:33386114
大小:1.79 MB
页数:37页
时间:2019-02-25
《多囊卵巢综合症(pcos)患者脂代谢及血纤溶能力变化的研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、分类号ICS学校代码!Q!墨鱼学号巡!垫蒌。萋一~菱.一§墓家喜民撤大学硕士学位论文多囊卵巢综合症;PCOS)患者脂代谢及血纤溶能力变化的研究StudiesonPolycysticOvarySyndrome(PCOS)PatientsLipidMetabolismandBloodFibrinolyticAbilityofChange申请人:学科专业:研究方向:学位类别:指导教师:王洪娟中西医结合临床蒙西医结合妇科学学术学位王霭明教授论文提交日期:二O一二年四月摘要目的分析多囊卵巢综合症(polycysticovarysyndrome,PC
2、OS)患者血脂、凝血指标的变化,探讨其对血管病变的影响及在PCOS诊治中的临床意义。方法选取78例多囊卵巢综合症患者及58例『F常对照组,测定凝血指标PT、APTT、FIB、PAI.1、t-PA、PC、PS和vWF的值,将数值按年龄、体重指数和胰岛素抵抗指数分为三个组别后,分别把PCOS患者和『F常人进行比较,采用spssl6.0进行统计学分析。结果按BMl分组显示:FIB、PC、vWF在两组别比较中均有差异(P0.0
3、5)。按工R值分组显示:FIB于IR组合非IR组均有统计学意义(P4、;PS和tPA于两个组别的比较中均无差异(P>O.05)。结论PCOS患者存在血脂功能紊乱,与正常人群相比凝血功能亢进,抗凝血功能、纤溶功能及血管内皮功能均减弱。关键词:多囊卵巢综合症;血脂;凝血;抗凝;纤溶;StudiesonPolycysticOvarySyndrome(PCOS)PatientsLipidMetabolismandBloodFibrinolyticAbilityofChangeAbstractObjectiveToAnalysisthechangesoftheindexoflipidmetabolismandcoag5、ulationparametersforPCOSpatients,toevaluatetheinfluenceofvascularlesionsandtheclinicalsignificanceinpolycysticovarysyndrome(PCOS)diagnosisandtreatment.MethodsEighty.eightPCOSpatientsandsixty—sevencontrolgroupweredividedrespectivelyintothreegroups.Determinationofbloodlipid6、andcoagulationparametersinpatientswithPCOScomparedwithcontrolsforstatisticalanalysis.ResultsAccordingtoBMIgroupshow:FIB,PC,vWFintwogroupsarecomparingthedifference(P<0.05),andPT,PAI,tPA,APTTonlyinobesitygroupshavedifference(P7、icsdifference(P>0.051).AccordingtoIRvaluesgroupshow:FIBinIRcombinationtheIRgrouparestatisticallysignificant(P<0.05)ingroupofIRFIBmeaningmoreobvious(P8、meVWFstatisticalsignificancemoresignificant俾
4、;PS和tPA于两个组别的比较中均无差异(P>O.05)。结论PCOS患者存在血脂功能紊乱,与正常人群相比凝血功能亢进,抗凝血功能、纤溶功能及血管内皮功能均减弱。关键词:多囊卵巢综合症;血脂;凝血;抗凝;纤溶;StudiesonPolycysticOvarySyndrome(PCOS)PatientsLipidMetabolismandBloodFibrinolyticAbilityofChangeAbstractObjectiveToAnalysisthechangesoftheindexoflipidmetabolismandcoag
5、ulationparametersforPCOSpatients,toevaluatetheinfluenceofvascularlesionsandtheclinicalsignificanceinpolycysticovarysyndrome(PCOS)diagnosisandtreatment.MethodsEighty.eightPCOSpatientsandsixty—sevencontrolgroupweredividedrespectivelyintothreegroups.Determinationofbloodlipid
6、andcoagulationparametersinpatientswithPCOScomparedwithcontrolsforstatisticalanalysis.ResultsAccordingtoBMIgroupshow:FIB,PC,vWFintwogroupsarecomparingthedifference(P<0.05),andPT,PAI,tPA,APTTonlyinobesitygroupshavedifference(P7、icsdifference(P>0.051).AccordingtoIRvaluesgroupshow:FIBinIRcombinationtheIRgrouparestatisticallysignificant(P<0.05)ingroupofIRFIBmeaningmoreobvious(P8、meVWFstatisticalsignificancemoresignificant俾
7、icsdifference(P>0.051).AccordingtoIRvaluesgroupshow:FIBinIRcombinationtheIRgrouparestatisticallysignificant(P<0.05)ingroupofIRFIBmeaningmoreobvious(P8、meVWFstatisticalsignificancemoresignificant俾
8、meVWFstatisticalsignificancemoresignificant俾
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