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1、ElectronicPosters:Diffusion&PerfusionDiffusionMRIHallBMonday14:00-16:00Computer5414:003964.ValidatingValidators:AnAnalysisofDW-MRIHardwareandSoftwarePhantomsPauloRodrigues1,VesnaPrckovska1,W.L.P.M.Pullens2,GustavJ.Strijkers3,AnnaVilanova1,BartM.terHaarRomeny11BiomedicalI
2、mageAnalysis,EindhovenUniversityofTechnology,Eindhoven,NoordBrabant,Netherlands;2MaatrichtBrainImagingCenter,MaastrichtUniversity,Maastricht,Limburg,Netherlands;3DepartmentofBiomedicalEngineering,EindhovenUniversityofTechnology,Eindhoven,NoordBrabant,NetherlandsDiffusion
3、WeightedMRItechniquessuchasDiffusionTensorImaging(DTI)andHighAngularResolutionDiffusionImaging(HARDI)areemergingMRItechniquesabletodepictin-vivobrain’sconnectivitymap.Thereisawiderangeofusesofthesetechniques;however,theirapplicationinaclinicalsettingrequiresthoroughvalid
4、ation.ThisworkaimstovalidateDTIandHARDIsoftwarephantoms,inregionsofsingleandcomplexfiberbundles,w.r.ttohardwarephantomandin-vivohumanbraindata.Knowledgeoftheaccuracyofsyntheticdatacanimprovetheevaluationofsuchalgorithms,andadvancetheemploymentofDTIandHARDIintoclinicalenv
5、ironment.14:303965.DiffusionImagingandTractographyonaHardwareModeloftheHumanOpticChiasmWilhelmusLPMPullens1,AlardRoebroeck1,RainerGoebel11FacultyofPsychologyandNeuroscience,MaastrichtUniversity,Maastricht,Limburg,NetherlandsThehumanopticchiasmisaninteresting,complexfiber
6、structure,hardtoimageinvivo.Basedontheanatomy,aDW-MRIphantomwasconstructed,offeringthepossibilitytoquantifytractographyresults,withlittlelimitsonimagingtime,anditdoesnotsufferfrommotionorcardiacpulsationartifacts.AdetailedanalysisofConstrainedSphericalDeconvolutionandten
7、sorreconstructionswasdone,aswellasquantitative(probabilistic)fibertracking.ThesephantomsformidealtestobjectstoimproveandvalidateimagingandquantitativeDW-MRItractographyoncomplexfiberstructuressuchastheopticchiasm.15:003966.DiffusionPropertiesofCorticalLayersinFixedHumanB
8、rainTissueInvestigatedwithHigh-ResolutionSTEAMAna-MariaOros-Peusquens1,ArladRoebroeck2,OlegPosnansky1,N
