舒心方治疗冠心病（气虚血瘀型）左室舒张功能减退的临床研究

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1、提要目的：观察舒心方治疗冠心病（气虚血瘀型）左室舒张功能减退的临床疗效，并探讨其部分作用机制，验证舒心方治疗冠心病（气虚血瘀型）左室舒张功能减退的临床疗效。方法：随机选择冠心病（气虚血瘀型）的患者60例，分为实验组30例和对照组30例。分别给予舒心方和芪参益气滴丸治疗，4周为一疗程，一个疗程后观察疗效。结果：冠心病治疗总有效率试验组为70.0%，对照组为56.7%，试验组优于对照组（P＜0.05）；中医证候改善情况，试验组总有效率90.0%，对照组为66.7%，试验组优于对照组（P＜0.01）；超声心动图疗效，试验组总有效率70.0%，对照组总有效率46.6%，试验组优于对照组

2、（P＜0.05）。结论：舒心方是临床上治疗冠心病（气虚血瘀型）的一个安全、有效的中药方剂，能明显改善胸闷、气短、胸痛、乏力等临床症状，有效改善患者心电图，改善超声心动图指标，其作用机理可能与扩张冠状动脉，改善心肌缺血、抗凝、降低心肌耗氧量、改善动脉粥样硬化的危险因素等有关。本试验提示：益气活血通脉是治疗冠心病（气虚血瘀型）的有效方法。关键词冠心病（气虚血瘀型）；舒心方；左室舒张功能；临床研究；中医药治疗Shuxinprescriptionstreatmentofcoronaryarterydisease(qideficiencyandbloodstasis)leftventri

3、culardiastolicfunctiontodropclinicalresearchSpeciality：InternalmedicineofTCMAuthor：ZouZhihaoTutor：Pro.SuWenGeAbstractObjective：Observeshuxinprescriptionstreatmentofcoronaryarterydisease(qideficiencyandbloodstasis)leftventriculardiastolicfunctiontodroptheclinicalcurativeeffect,anddiscussesthe

4、irpartoftheactionmechanism,validationshuxinsidetreatmentofcoronaryarterydisease(qideficiencyandbloodstasis)leftventriculardiastolicfunctiontodroptheclinicalcurativeeffect.Methods：Randomselectionofcoronaryheartdisease(qideficiencyandbloodstasis)were60cases,dividedintothe30casesand30casesin.We

5、regivenshuxinprescriptionsandQishenyiqidroppingtreatment,4weeksforaperiodoftreatment,afteraperiodoftreatmentobservationcurativeeffect.Results：Respectively,thetotalanginaeffectiverateis70.0%inexperimentgroupand56.7%incontrolgroup,thecomparisonofthetwogroupshasstatisticsignificance(P＜0.05),the

6、experimentgroupshowsbetterthanthatincontrolgroup;thetotaleffectiverateofthesymptomsontraditionalChinesemedicineis90.0%,66.7%(P＜0.01);echocardiographytotaleffectiverateis70.0%,46.6%;twogroupshaveremarkabledifference(P＜0.05).Conclusions：Shuxinprescriptionsisclinicallytreatmentofcoronaryheartdi

7、sease(qideficiencyandbloodstasis)ofasafeandeffectiveproprietaryChinesemedicine,canobviouslyimprovethechesttightness,shortnessofbreath,chestpain,andthelackofclinicalsymptoms,effectivelyimprovethepatientselectrocardiogram,improveechocardiographyindex