耳穴治疗高脂血症随机对照临床研究文献meta分析

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1、耳穴治疗高脂血症随机对照临床研究文献Meta分析李欢李桂平天津中医药大学天津中医药大学第一附属医院针灸摘要：目的系统评价耳穴治疗高脂血症的临床疗效。方法计算机检索中国知网数据库(CNKI)、维普全文期刊数据库(VIP)、万方数据库(WanFangData)、PubMed、WebofScience>EMbase>MEDLINE(Ovid)和CochraneLibrary等数据库，搜集耳穴治疗高脂血症的相关临床随机对照试验(RCT),检索时限均从建库至2016-12-3K由2名研究者独立筛选文献、提取资料和评价纳入研究的偏倚风险后，采用RevMan5.3软件进行Meta分析。

2、结果共纳入9篇随机对照试验，包括1115例患者。Meta分析结果:从总有效率来看，耳针联合中西药与单纯中西药降脂疗效相似，耳穴联合改变生活方式的降脂疗效优于单纯改变生活方式降脂，耳针与西药降脂疗效相似，耳穴联合体针的降脂疗效优于单纯体针降脂。结论耳穴降脂有一定疗效且相对安全。但因纳入试验数有限且文献质量较低，需要设计更严格的随机对照试验来进一步验证上述结论。关键词：耳穴贴压;高脂血症;穴位疗法;Met。分析;作者简介：李欢(1991—),女，硕士研究生在读。研究方向:针灸推拿学。收稿日期：2017-07-05Randomizedcontrolledtrialsofauri

3、cularpointforhyperlipidemia:AMeta-analysisLIHuanLIGuipingTianjinUniversityofTraditionalChineseMedicine;Abstract：ObjectiveTosystematicallyassesstheclinicaleffectsofauricularpointonthetreatmentofhyperlipidemia.MethodsWeelectronicallysearcheddatabasesincludingCNKI,VIP,WanFangData,PubMed,Webo

4、fScience,EMbase,MEDTTNE(Ovid),andCochraneLibrarytocollectremdomizcdcontrolledtrials(RCT)ofauricularpointforhyperlipidemiafrominceptiontoDecember31,2016.Tworeviewersindependentlyscreenedliterature,extracteddataandassessedtheriskofbiasofincludedstudies.Then,meta-analysiswasperformedbyusingR

5、evMan5.3software.ResultsAtotalof91iteraturesand1115patientswereincluded.TheResultsofMcta-analysisindicated:intcrmsofthetotedeffectivcrate,theauricularneedlecombinedwithChineseandwesternmedicine,andsimpleChineseandwesternmedicinehavesimilareffectsonlipid-lowering.Thelipid-loweringeffectofa

6、uricularpointcombinedwithchangingthe1ifestyleisbetterthansimplychangingthe1ifestyle.Auricularpointandwesternmcdicinchavesimilareffectsonlipid-lowering.Thelipid-loweringeffectofauricularpointcombinedwithbodyacupunctureissuperiortothesimplybodyacupuncture.ConelusionAuriculariapointhasacerta

7、inefficacyandrelativelysafeon1ipid-lowering.However,duetothelimitednumberoftrialsandthelowqualityoftheliterature,amorerigorousremdomizedcontrolledtrialisneededtofurthervalidatetheaboveConclusions.Keyword：Auricularpressure;Hyperlipemia;Acupointtherapy;Metaanalysis;Re