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1、提要目的:本论文旨在从营卫理论探讨失眠症的发生机理并观察加味柴胡桂枝汤治疗失眠症的临床疗效。方法:本研究从临床选取营卫不和、气机失调型失眠症患者60例,随机分为两组,治疗组30例,对照组30例。治疗组给予加味柴胡桂枝汤,对照组给予舒眠胶囊,疗程均为4周。观察治疗前后PSQI量表、中医临床证候评分的变化。结果:经统计学分析,两组在治疗前一般资料包括性别、年龄、PSQI积分、中医临床证候评分无明显统计学差异,具有可比性。治疗后两组在PSQI量表、中医临床证候评分较治疗前均有改善,但治疗组在改善睡眠质量、日间功能、睡眠时间、睡眠效率、睡眠障碍方面优于对照组,且治疗
2、组能显著改善失眠症患者伴发的晨起困倦、心烦或躁、昼日精神萎靡、四肢倦怠、汗出等兼症。结论:加味柴胡桂枝汤治疗营卫不和、气机失调型失眠症,与舒眠胶囊组进行对照观察,两组在PSQI量表及中医临床证候积分方面比较,加味柴胡桂枝汤组显著优于对照组,证明加味柴胡桂枝汤治疗营卫不和、气机失调型失眠症具有较好的临床实用性。关键词失眠症;营卫不和、气机失调;加味柴胡桂枝汤;临床观察ThemechanismandclinicalstudyofmodifiedChaihuGuizhidecoctioninthetreatmentofinsomniabasedonthetheor
3、yofYingandWeiSpeciality:NeurologydepartmentofTCMAuthor:SuiXiaoLinTutor:ProfessorWangZhong-linAbstractObjective:ThisthesisfromthetheoryofYingandWeigovernancemechanismofmodifiedChaihuGuizhiDecoctioninthetreatmentofinsomniaanditsclinicaleffectobservationonthetreatmentofinsomnia.Method
4、s:Inthisstudy,selectedfromtheclinicalYingandWeitesty,DisorderofmovementofQitype60patientswithinsomniawererandomlydividedintotwogroups,treatmentgroup30cases,30casesofthecontrolgroup.ThetreatmentgroupreceivedmodifiedChaihuGuizhiDecoction,ControlgroupgivenShuMiancapsules,acourseof4wee
5、ks.PSQIscalebeforeandaftertreatment,TCMsyndromescorechanges.Results:Statisticalanalysis,thetwogroupsbeforetreatment,generalinformationincludinggender,age,PSQIpoints,TCMsyndromeandsohavenosignificantdifference,comparable.AftertreatmentinthePSQIscale,TCMtermsofsymptomscoreswereimprov
6、edcomparedwithbeforetreatment,butTreatmentgroupinimprovingsleepquality,dayfunction,sleep,sleepdisorders,sleepefficiencyisbetterthanthecontrolgroupandcansignificantlyimproveinsomniatreatmentgroupspatientswithearlymorningdrowsiness,upsetormania,dayspiritofweak,limbs,suchasfatigue,swe
7、ating.Conclusion:TheuseofadjustedmodifiedChaihuGuizhidecoctiontreatinginsomniaofYingandWeitesty,DisorderofmovementofQi,andwithShuMiancapsuleswereobservedcapsulegroup,twoinPSQIpoints,andchangesinclinicalsymptomscore,theadjustedmodifiedChaihuGuizhidecoctiontreatedgroupwassignificantl
8、ybetterthanthecontrolgroup