不同药物联合硬膜外麻醉对术中应激的影响

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1、郑州大学2009届硕士学位论文不同药物全麻联合硬膜外麻醉对患者应激反应的影响英文摘要EffeetsofdifferentanestheticscombindwithePiduralanaesthesiaonstressreactionofPatientsundergoingoPerationsofesoPhagealCanCinonlaStudent:Li丫乞21TUtor:HanXuePingD印artmentofanesthesiology，thefirstaffiliatedhosPitalo

2、fZhengZhouUniversityZhengZhouChina450052Background:FormajorityPatiensofesoPhageetomyinelderly，theirirn们nunefunetionandcomPensatoryfunctionareless，butcomPlieationsaremore.one一lungventilation(OLv)techni叨e15inereasinglybeingusedfortheradiealeorrectionofes

3、opha，searcinoma.But，ThoraeieSurgeryorOne一lungventilation(OLV)indueesstronglystressresponseandaPro一infl田旧们natoryresponseineludingeytokinerelease、leucoeyterea刀itmentandstressreaetionhormonereleaseintheventilatedlung.Theseresponswouldindueetheehangesofres

4、Piratorysystetn，eirculatorysystem，nerves-即docrine一inununesystem伽El).ThemajorityPationsofmalignanttumorexistirn们nunedisfunction.StressreactionindueedbyoPerationwouldleadtoi们n们nune几nctiondeerease，thatwouldresultinsurvivalrateofcyto一mieroembolusinereasing

5、.Thesewouldleadtotumoreellgrowthandtumormetastasis.EventhoughstressreactionmajorindueedbyoPerationstimulus，butsuitablecomPatibilityofanesthetiedrugsormethodsarebenefitforcontrolingstressreaetiond而ngoPerationandimProvingPationsi们n们nunestate.Remifentanil

6、15arelativelynew林一oPiatereeePtoragonistandthefirstsuPer一short一PotencyoPioiddrug.Thestableeliminationrateofre们nifentanilfitintheliverorkidneydysfunctionandtheelderlyPoPulationforalongtimeanthesiawithoutVI郑州大学2009届硕士学位论文不同药物全麻联合硬膜外麻醉对患者应激反应的影响英文摘要havingt

7、oconsidertheProblemofdruginlhaionacc切mulation.But，thereareafewprob】emsd而nganesthesiawithr。爪们nifentanil.Theinhibitoryeffectofanaestheticstressresponsemayd即即dupontheirdose，esPeeiallywhenusingai.v.orvolatileagent.IntraOPerativeandPostoPerativei刊比bitiononh

8、eartfimctioninhibitionduetohigh一doseremifentainilorsevofluranewouldleadtothecomPlicationinduced:bradycardia，lowc田过iaeoutPut，fluctuationofhemod”aznies，museleofthoraxb以刀mingstiff，and50on.TheotherProblem15thatPainriseatPostoPerativeearlier