vcind患者中医证候与mrs变化的分析

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1、AbstractdromesandVascuIarObjectlye：ToexplorethedifferencesoftheTCMsyndrome(typeofkidneyessencevacuityandphlegmblockingorificestype)inmagneticresonancespectroscopy(MRS)ofpatientswithvascularcognitiveimpairmentnon—demented(VCIND)Methods：Wescreenedthe45-84year——oldpatientsinoutpat

2、lentandinpatlentdepartmentofChinesemedicinehospitalofHubeiProvincefromtheOctoberof2010totheFebruaryof2012，aprofesSionalpractitlonerofChineseencephalopathyunifiedits1ineofTClVltheHourating(SDSVD)，elinicaldementiaRatingScale(CDR)score，theMini-Menta1Examination(MMSE)score，activiti

3、esofdaily1iving(ADL)wereHaljinsijiischemicindex(Hachinski)scoreratingdepressionScale(HMD)，HanMisecretMontrealcognitivefunction(MoCA)score，accordingtotheresultS，andrefertothediagnosticcriteriabythepreviousresearchersofVCIND，wescreenedthepatientSwithvascularcognitiveimpairmentnon

4、—。typedementia(VCIND)42cases，including13casesofpatlentSwithdeficiencyofkidneyessence，and13casesofthepatientswithIIIphlegmblockingtheorifices，includedin15casesofhealthyolderadultSinthe1ightoftheelderlyhea1thStandardsdevelopedbytheWHOasnormalcontrolgroup，accordingtotheStatiStical

5、analysiS，therewasnosignificantdifference(P<0．05)ofthegenera1information，likegender，age，educationlevelandectofthethreegroups．Theselectedofthesethreegroupswereperformedonbrainmagneticresonancespectroscopy(MRS)examination，wemeasurementtheNAA，Cho，CrandNAA／CrinCho／Crratioofthebilate

6、ralhippocampus，frontallobe，thalamus，angulargyrusandtheCingulate．A11subjectswereright—handed，andSignedinformedconsentbeforeenr01lment．Results：comparedtothecontrolgroup，wefoundthattheperformanceofmagneticresonancespectroscopy(MRS)inthepatientSofVascularcognitiveimpairmentwithoutd

7、ementia(VCIND)’SNAA／CrratiodecreasedSignificantlyinthethalamusandrightposteriorCingulate，theCho／Crvaluesincreasedintherightfrontallobe，whilecomparedwiththecontrolgroup、theNAA

8、CrandCho

9、吐valuesinhippocampusandtheangulargyrus’SdifferencewasnotStatistica1lySignificant；which，compare

10、dwiththecontrolgroup，blockingtheorificesgrouptherightS