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1、第三军医大学硕士学位论文rhythmandclinicalandpathologicalmanifestationstorevealtheclinicalsignificanceandinfluencingfactorsofabnormalbloodpressurerhythmsinCKDpatients,whichwillpresentanimportantclinicalvalueinpreparationofcomprehensivepreventionstodelaytheprogressionofchronickidneyd
2、iseasesandreducethemorbilityandmortalityofcardiovascularevents.Methods:FromJanuary2011toOctober2012,427casesofprimaryIgANswerediagnosedthroughrenalbiopsyinNephrologyDepartmentofDapingHospital(patientage:18-69years).A24hdynamicbloodpressuremonitoringwasperformedforallthe
3、patients,and[13]theirbloodpressureandrhythmswereevaluatedinaccordancewithJNC7hypertension[14]diagnosisstandardandthediagnosisstandardofbloodpressurecircadianrhythm.First,aresearchwasconductedonthetotalincidenceofabnormalbloodpressurerhythminallthepatientsandthedistribut
4、ioncharacteristicsofabnormalbloodpressurerhythminpatientswithdifferentsex,agegroupandmedication.Afterexclusionofthepatientscombinedwithdiabetesmellitus,acuteinterstitialrenaldamageandadministrationofglucocorticoidsandantihypertensivedrugs(86cases),acollectionwasconducte
5、din341patients,includingclinicaldata,renalpathologydiagnosisinformationandbloodandmorningurineonthedayofbloodpressuremonitoringaswellas24hurinespecimen.Atotalof50indexesareincluded,including9itemsofclinicaldata(sex,age,height,bodyweight,BMI,courseofdisease,medicalhistor
6、y,previousmedicationsandsmokinghistory),23laboratoryindexes(hepatorenalfunction,bloodlipid,bloodglucose,urinebiochemistry,urineprotein/creatinineandurinaryNAGenzyme)and18renalhistological[15]indexes(OxfordIgANclassificationandscoringandimmunopathogenesisindexes).Themeas
7、urementdataareexpressedasmean±SD,andtheclassifiedvariablesareexpressedasarate.Thecomparisonofmeasurementdatabetweenbothgroupswasconductedbyttest,2thecountingofdatawasperformedbyXtest,andtheclassificationdatawereanalyzedbyRiditmethod.Thestudyadoptedtheunivariateandmultiv
8、ariatelogisticregressionanalysistoinvestigatetheinfluencingfactorsofbloodpressurecircadianrhythmsinIgANpatient
