欢迎来到天天文库
浏览记录
ID:32227121
大小:1.07 MB
页数:29页
时间:2019-02-01
《喉癌复发相关因素与治疗临床分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、喉癌复发相关因素与治疗临庶分析硕士礤究生:指导教师:专韭名棼:郭燕佟凯教授耳鼻咽喉科学摘要目的:探讨喉癌峻床复发的相关因素积治疗效果及预后。方法:回顾性分析1995.2003年我院经治的22例复发性喉癌患者鲍基本概提。冀中声门型13铡,声门上型9例;原发黔癯行全喉切除的6例,部分喉切除的16例;(21例在我院初次手术;1例为外院手术后复发转入)。复发性喉癌根据不同病情采取不阉手术方法。全部痰例均有随访。应用Kaplan.Meier法进行生存分析。结果:喉瘀患者的复发郡位包括局部复发、颈部淋巴结复发及远处转移;喉鳞癌复发的时间为3-38个月,中位时间为15个月;局部复发8
2、侧,颈郝淋巴结复发7例,5例为局部并颈部淋巴结复发,2例为远处转移;喉癌囱初次术后3年生存率为62.4%,5年生存率为36.4%。复发术后3年生存率为24。6%,5年生存率为1%。主要并发痰为切口感染和咽漏;术后均可经口进食,经造瘘粕呼吸通畅。结论:喉瘢术后复发的赢接相关因素主要是术式的恰当选择和颈部淋巴结转移的正确处理。受发性喉癌预后较差,治疗上以手术为主,辅以放射及化学治疗。喉癌术后应及时密切随访,定期行影像学复查,达到早期发现早期治疗的目的。关键谲:喉切除术喉肿瘤复发预后Clinicalanalysisofrelevantfactorsandtherapyofla
3、ryngealcarcinormapostoperativerecurrencePostgraduate:GuoyanSupervisor:TongkaiSpeciality:OtorhinolaryngologyAbstractobieetive:Toevaluatetheclinicalrelatedfactorsofrecurrentlaryngealcarcinomaanddevelopedtherapeuticeffect,andtoinvestigatetherapyandtheprognosticfactorsofrecurrentlaryngealcar
4、cinoma。Methods:Theclinicalrecurrentfactorsandtherapeuticeffectofrecurrentlaryngealcarcinomafrom1995to2003wereanalysedretrospectively.13casesoflaryngealcarcinomaweresupraglotticcarcinoma;9casesoflaryngealcarcinomawereglotticcarcinoma;16casesofprimarycarcinomaweretreatedbypartiallaryngecto
5、my,and6casesofprimarycarcinomaweretreatedbytotallaryngectomy(21caseswerefirstlyoperatedinourhospital,anotheroneWaspostoperativerecurrenceinotherhospital>;Thepatientswithrecurrentlaryngealcarcinomawereadoptedtothedifferentoperationonthebasisofthedifferentpathogeneticcondition.Survivalanal
6、ysiswasperformedbyKaplan-Meiermethod;Results:Therecurrencesitesincludedlocoregionalrecurrence,necklymphnodeanddistantmetastasee.The3-yearand5-yearoverallsurvivalrates&rpatientswithlaryngealcarcinomawere62.4%and36+4%.The3-yearand5-yearoverallsurvivalratesforpatientswithrecurrentlaryngealc
7、arcinomawere24。6%andl%.Therecurrenceoflaryngealcarcinomaweredevelopedwithin3-38months,themediantimeofrecurrencewas15months;therewere8locoregionalrecurrence,7necklymphnoderecurrence,5locoregionalrecurrenceassociatedwithnecklymphnoderecurrence,2distantmetastases;礴emaincompl
此文档下载收益归作者所有