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ID:32187795
大小:2.72 MB
页数:48页
时间:2019-02-01
《抗血小板药物对脑卒中不同essen评分患者的二级预防效果分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、万方数据浙江大学硕士学位论文英文摘要12.07%,P。0.001).5Aboutthesafetyofaspirinorclopidogrelusedstrokepatients:whenESRS<3,theadversereactionsratesofGroupaspirinwashigherthanthatGroupclopidogrel(13.25%:7.41%,P=0.369),butthereisnostatisticaldifferencebetweenofthem;whenESRS=3,theadversere
2、actionsratesofGroupaspirinwashigherthanthatofGroupclopidogrel(12.57%:8.00%,P=0.296),butthereisnostatisticaldifferencebetweenofthem;whenESRS>3,thereWasnodifferenceofadversereactionsratesbetweenGroupaspirinandGroupclopidogrel(6.93%:7.10%,P=0.947).6Tofurtherexploremul
3、tivariatevariablesanalysis:whenESRS<3.thedrugwithdrawalrateofantiplateletdrugs[OR=3.471,95%CI(1.222,9.859),P=0.019】wastheindependentfactorofstrokerecurrence;whenESRS=3,theantiplateletdrugselectionofaspirinorclopidogrel[OR=0.432,95%CI(0.229,0.814),P=0.009]andthedrug
4、withdrawalrateofantiplateletdrugs【OR=2.063,95%CI(1.103,3.859),P2O.023]weretheindependentfactorsofstrokerecurrence;whenESRS>3,theantiplateletdrugselectionofaspirinorclopidogrel【OR=2.035,95%CI(1.208,3.430),P=O.008]andthedrugwithdrawalrateofantiplateletdrugs[OR=2.415,
5、95%CI(1.119,5.214),P=0.025】weretheindependentfactorsofstrokerecurrence.Conclusions:1WhenESRS<3,thedrugwithdrawalrateofGroupaspirinWassignificantlylowerthanthatofGroupclopidogrel,butthereisnodifferenceinthevascularendpointevent,neurologicalfunctionimproving,safetybe
6、tweeninthesetwogroups.Thus,choosingaspirinforsecondarypreventionofstrokecomparedismoreappropriatetoclopidogrel.2WhenESRS=3,thevascularendpointeventofGroupaspirinWassignificantlylowerthanthatofGroupclopidogrel,thedrugwithdrawlrateofGroupaspirinWassignificantlylowert
7、hanthatofGroupclopidogrel,buttherewerenodifferenceneurologicalfunctionimprovingandthesafetybetweenofthem,Thus,choosingaspirinforsecondarypreventionofstrokeismoreappropriatetoclopidogrel.3WhenESRS>3,theincidenceofvascularendpointeventofGroupclopidogrelVIl万方数据浙江大学硕士学
8、位论文英文摘要wassignificantlylowerthanthatofGroupaspirin,andtheneurologicalfunctionimprovingwassignificantlybetterthanthatofGroupaspirin,butthereisnodi
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