抗血小板药物对脑卒中不同essen评分患者的二级预防效果分析

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1、万方数据浙江大学硕士学位论文英文摘要12．07％，P。0．001)．5Aboutthesafetyofaspirinorclopidogrelusedstrokepatients：whenESRS<3，theadversereactionsratesofGroupaspirinwashigherthanthatGroupclopidogrel(13．25％：7．41％，P=0．369)，butthereisnostatisticaldifferencebetweenofthem；whenESRS=3，theadversere

2、actionsratesofGroupaspirinwashigherthanthatofGroupclopidogrel(12．57％：8．00％，P=0．296)，butthereisnostatisticaldifferencebetweenofthem；whenESRS>3，thereWasnodifferenceofadversereactionsratesbetweenGroupaspirinandGroupclopidogrel(6．93％：7．10％，P=0．947)．6Tofurtherexploremul

3、tivariatevariablesanalysis：whenESRS<3．thedrugwithdrawalrateofantiplateletdrugs[OR=3．471，95％CI(1．222，9．859)，P=0．019】wastheindependentfactorofstrokerecurrence；whenESRS=3，theantiplateletdrugselectionofaspirinorclopidogrel[OR=0．432，95％CI(0．229，0．814)，P=0．009]andthedrug

4、withdrawalrateofantiplateletdrugs【OR=2．063，95％CI(1．103，3．859)，P2O．023]weretheindependentfactorsofstrokerecurrence；whenESRS>3，theantiplateletdrugselectionofaspirinorclopidogrel【OR=2．035，95％CI(1．208，3．430)，P=O．008]andthedrugwithdrawalrateofantiplateletdrugs[OR=2．415，

5、95％CI(1．119，5．214)，P=0．025】weretheindependentfactorsofstrokerecurrence．Conclusions：1WhenESRS<3，thedrugwithdrawalrateofGroupaspirinWassignificantlylowerthanthatofGroupclopidogrel，butthereisnodifferenceinthevascularendpointevent，neurologicalfunctionimproving，safetybe

6、tweeninthesetwogroups．Thus，choosingaspirinforsecondarypreventionofstrokecomparedismoreappropriatetoclopidogrel．2WhenESRS=3，thevascularendpointeventofGroupaspirinWassignificantlylowerthanthatofGroupclopidogrel，thedrugwithdrawlrateofGroupaspirinWassignificantlylowert

7、hanthatofGroupclopidogrel，buttherewerenodifferenceneurologicalfunctionimprovingandthesafetybetweenofthem，Thus，choosingaspirinforsecondarypreventionofstrokeismoreappropriatetoclopidogrel．3WhenESRS>3，theincidenceofvascularendpointeventofGroupclopidogrelVIl万方数据浙江大学硕士学

8、位论文英文摘要wassignificantlylowerthanthatofGroupaspirin，andtheneurologicalfunctionimprovingwassignificantlybetterthanthatofGroupaspirin，butthereisnodi