颅底脑膜瘤手术治疗与并发症的相关因素分析

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1、天津医科大学硕士学位论文目录中文摘要„„„„„„„„„„„„„„„„„„„„„„„„„„„„„ⅠAbstract„„„„„„„„„„„„„„„„„„„„„„„„„„„„„Ⅲ缩略语/符号说明„„„„„„„„„„„„„„„„„„„„„„„„„Ⅶ前言„„„„„„„„„„„„„„„„„„„„„„„„„„„„„„„1研究现状、成果„„„„„„„„„„„„„„„„„„„„„„„„„1研究目的、方法„„„„„„„„„„„„„„„„„„„„„„„„„11.对象和方法„„„„„„„„„„„„„„„„„„„„„„„„„„31.1研究

2、对象„„„„„„„„„„„„„„„„„„„„„„„„„31.1.1临床表现„„„„„„„„„„„„„„„„„„„„„„„31.1.2既往病史······································································31.1.3术前影像资料„„„„„„„„„„„„„„„„„„„„„31.1.4手术情况······································································51.1.5

3、并发症·········································································71.2统计分析方法„„„„„„„„„„„„„„„„„„„„„„„„72.结果„„„„„„„„„„„„„„„„„„„„„„„„„„„„„82.1一般情况和切除程度关系„„„„„„„„„„„„„„„„„„82.2术前状态和切除程度关系„„„„„„„„„„„„„„„„„„82.3术前影像和切除程度关系„„„„„„„„„„„„„„„„„„102.4术中所见情况和切除程度

4、关系„„„„„„„„„„„„„„„„112.5切除程度的多因素„„„„„„„„„„„„„„„„„„„„„122.6一般情况和神经系统并发症关系„„„„„„„„„„„„„„„122.7术前状态和神经系统并发症关系„„„„„„„„„„„„„„„132.8术前影像和神经系统并发症关系„„„„„„„„„„„„„„„142.9术中所见情况和神经系统并发症关系„„„„„„„„„„„„„152.10神经系统并发症的多因素„„„„„„„„„„„„„„„„„„163.讨论„„„„„„„„„„„„„„„„„„„„„„„„„„„„„1

5、73.1概述„„„„„„„„„„„„„„„„„„„„„„„„„„„173.2资料结果分析„„„„„„„„„„„„„„„„„„„„„„„183.3病理亚型与切除程度和并发症关系„„„„„„„„„„„„„„26V万方数据天津医科大学硕士学位论文3.4神经系统并发症具体分析„„„„„„„„„„„„„„„„„„283.5复查„„„„„„„„„„„„„„„„„„„„„„„„„„„31结论„„„„„„„„„„„„„„„„„„„„„„„„„„„„„„33参考文献„„„„„„„„„„„„„„„„„„„„„„„„„„„„34发表论

6、文和参加科研情况说明„„„„„„„„„„„„„„„„„„„39综述„„„„„„„„„„„„„„„„„„„„„„„„„„„„„„40颅底脑膜瘤诊治的研究进展„„„„„„„„„„„„„„„„„„„40综述参考文献„„„„„„„„„„„„„„„„„„„„„„„„„44致谢„„„„„„„„„„„„„„„„„„„„„„„„„„„„„„47VI万方数据天津医科大学硕士学位论文缩略语CTComputedTomography计算机断层扫描DSADigitalSubtractionAngiography数字减影血管成像CTACom

7、putedTomographyAngiographyCT血管造影MRIMagneticResonanceImaging磁共振成像CPACerebellopontineanglearea桥小脑角CIConfidenceinterval置信区间MRVMagneticResonanceVenography磁共振静脉成像SRSStereotaxicRadioSurgery立体定向放射外科VII万方数据天津医科大学硕士学位论文前言研究现状、成果脑膜瘤（Meningioma）是起源于蛛网膜内皮细胞，可发生在任何含有蛛网膜成分

8、的部位。脑膜瘤在人群中的发现率约为每100000人中2.3人次，而在尸【1,2】检报告中每100000人中发生率为5.5人次。瘤基底与前、中、后颅窝底附着的脑膜瘤统称为颅底脑膜瘤。一般而言，颅底脑膜瘤诊断及治疗都较困难。颅神经均由颅底出颅，因此颅底脑膜瘤的颅神经损害多见，手术全切除肿瘤困难。对于大部分颅底脑膜瘤来说，手术治疗是首选的治疗手段。颅底脑膜瘤的手术治疗应在保障神