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ID:32134903
大小:2.36 MB
页数:60页
时间:2019-01-31
《fish技术在宫颈癌和乳腺癌检测中的临床应用分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、第三军医大学硕+学位论文主要英文缩写一览表英文缩写英文全称中文全称CINCervicalIntraepithelialNeoplasia宫颈上皮内瘤变CSPCentromereofchromosomeSpecialProbe染色体着丝粒探针DAPI4,6一diamidino-2一phenylindole4,6一二氨基一2.苯吲哚DFSDisease.freesurvival无病生存率FISHFluorescenceinSituHybridization荧光原位杂交GLPGenelocus.specialprobs位
2、点特异性探针HR-HPVHigh.riskhumanpapillomavirus高危型人类乳头瘤状病毒Her-2Humanepidermalgrowthfactorreceptor2人类表皮生长因子受体2HC-2HybridCaptureII杂交捕获法二代hTERCHumantelomeraseRNAgenecomponents人类端粒酶RNA基因组分hTERTHumantelomerasereversetranscriptase人类端粒酶逆转录酶ICCInvasiveCervicalCancer浸润性子宫颈癌ID
3、CInvasiveDuctalCarcinoma浸润性导管癌IHCImmunohistochemistry免疫组化NPVNegativePredictionValue阴性预测值OSOverallSurvival总生存率PCRPolymeraseChainReaction多聚酶链反应PPVPositivePredictionValue阳性预测值RTKReceptorTyrosineKinase受体酪氨酸激酶SeSensitivity敏感性SpSpecificity特异性TCTThin—prepCytologicalT
4、est薄层液基细胞学检测TBSTheBethesdaSystemforreportingcervical巴氏宫颈细胞学报告系统cytology第三军医人学硕十学位论文Fluorescenceinsituhybridization(FISH)fordetectionofcervixcancerandbreastcancer:aclinicalBackground_^●●·●researcll0I-aOOlicationAbstractCervixcancerandbreastcancerarefrequentgyne
5、cologicalmalignanttumorinrecentyears,theincidencesofwhichareonthetopinourcountry,withthetendencytoriseyearbyyear.Tothetreatmentandpreventionoftumors,theforemostprincipleisearlydiagnosisthenearlytreatment.Therefore,ontheprocessoftumorigenesisanddevelopment,thed
6、etectiontocytogeneticchanges,isanimportantmethodforearlydiagnosisandearlytreatmentoftumors,whichisofgreatsignificancetoimproveprognosisofpatientsandraiselifequality.Atpresent,theearlydiagnosisagainsttocervixcancer,mainlycontainscellmorphologyexamine,HPVvirusde
7、tection,andsomeothercommontumormarkerscreening.ThescreenforbreastcancerismainlyimageologicalexamineandIHCetc.Nevertheless,thetraditionalmethodscan’tsatisfythebothsideofsensitivityandspecificity.Fluorescenceinsituhybridization(FISH)isatechnologyconjunctofinsitu
8、molecularcytohybridizationandfluorescenttechnique,comparedwiththetraditionalcytogeneticaltechnique,whichhastheadvantagesofhighsensitivity,strongsignal,fast,convenienceandaccurateal
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