2型糖尿病患者下肢血管钙化特点与相关因素分析-(7314)

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1、东南大学硕士学位论文rnl1J●J●1’·’●■J一1l。neCnaraCtenStiCSannrelatelllaCtOrS0IVaSCUlar：alcifieation’lowerlimbsofpatientswithtype2calcilicationinerliml3sotPatients11ediabetesClinicalMedicine，Southe蠲tUniversityPostgraduateZHAOZhenMentorsJINHuiAbstractobjective：Theaimsofthisstudywastoinvestigatethech

2、aracteristicsandrelatedfactorsofvascularcalcificationinlowerlimbsofpatientswithtype2diabetes，SOastogetmoredatatoprovideagoodscientificbasisforclinicaldiagnosisandtreatmentforlower-extremityarterialdisease。Methods：204patientsdiagnosedwithtype2diabetesfromJanuary2007toDecember2012，which

3、werehospitalizedinZhongdaHospital，SoutheastUniversity,hadsufferedfromthesymptomsonlowerlimbandtookCTAtest．Wecollecttheirbasicinformation，suchasgender，age，diabetesduration，comorbiddiseases，complicationsandhistoryofsmoking．Wealsostudytheirbiochemicalindexsuchasglycatedhemoglobin，fibrino

4、gencontent，Ddimmer，triglycerides，totalcholesterol，high-densitylipoprotein，lowdensitylipoprotein，sertllTlcalcium，phosphorus，creatinine，UA(UricAcid)，urinemicroalbuminandcreatinine．AUthesymptomsandprognosisofpatientshadbeenrecorded．WegettheirABIdataofposteriortibialarteryanddorsalispedis

5、arterythroughdopplerultrasound．TwoexperiencedtechniciansstudythedistributionofcalcificationoneightperiodofvesselsinlowerlimbsthroughCTimaging．Andlastweanalysisthecollecteddata．Results：1．178patientshavebeenfoundvascularcalcificationintheirlowerlimbsof204padentswithtype2diabetes．101pati

6、entsaremaleandtheirmeanageiS68．99±9．512yearsoldwhosemeanCourseoftype2diabetesare11．54±8．092years,while77arefemalewith71．23±8．491yearsoldandhavethediseaseabout13．81±9．708years．2．Therateofhypertension。coronarydiseaseandcerebralinfarctionis65．69％，22．55％，32．35％respectively．Andtherateofthe

7、patientswithdiabeticnephropathy，neuropathy，angiopathyanddiabeticfootis25％，51．47％，49．02％，66．18％lV英文摘要respectively．AccordingtotheWagnerGrade，thereare5peopleinGrade0,4inGrade1，36inGrade2，45inGrade3。44inGrade4and2inGrade5．3．A11thepatientswecollectedhavetheelinicalsymptoms．18patientsfeelwe

8、aknes