蓝玉簪颗粒治疗慢性哮喘小鼠气道重建实验的研究

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1、分类号密级国际十进分类号（UDC）第四军医大学学位论文蓝玉簪颗粒治疗慢性哮喘小鼠气道重建的实验研究（题名和副题名）张力江（作者姓名）指导教师姓名李焕章教授(主任医师)指导教师单位第四军医大学西京医院呼吸内科申请学位级别硕士专业名称内科学(呼吸系病)论文提交日期2008.04答辩日期2008.05论文起止时间2006年7月至2008年4月学位授予单位第四军医大学独创性声明秉承学校严谨的学风与优良的科学道德，本人声明所呈交的论文是我个人在导师指导下进行的研究工作及取得的研究成果。尽我所知，除了文中特别加以标注和致谢的地方外，论文中不包含其他人已经发表或撰写过的研究成果，不包含本人或他人已申请学位或

2、其他用途使用过的成果。与我一同工作的同志对本研究所做的任何贡献均已在论文中作了明确的说明并表示了致谢。申请学位论文与资料若有不实之处，本人承担一切相关责任。论文作者签名：日期：保护知识产权声明本人完全了解第四军医大学有关保护知识产权的规定，即：研究生在校攻读学位期间论文工作的知识产权单位属第四军医大学。本人保证毕业离校后，发表论文或使用论文工作成果时署名单位仍然为第四军医大学。学校可以公布论文的全部或部分内容（含电子版，保密内容除外），可以采用影印，缩印或其他复制手段保存论文。学校有权允许论文被查阅和借阅，并在校园网上提供论文内容的浏览和下载服务。论文作者签名：导师签名：日期：蓝玉簪颗粒治疗慢

3、性哮喘小鼠气道重建的实验研究硕士研究生：张力江学科专业：内科学（呼吸系病）所在单位：第四军医大学西京医院呼吸内科导师：李焕章教授(主任医师)资助基金项目：关键词：慢性哮喘；气道重建；动物模型；小鼠；蓝玉簪龙胆；转化生长因子-β1；Bcl-2中国人民解放军第四军医大学西京医院呼吸内科2008年05月西安第四军医大学硕士学位论文目录缩略语表············································································································1中文摘要··················

4、··························································································3英文摘要············································································································7前言······························································································

5、············12文献回顾··········································································································14第一部分慢性哮喘小鼠模型的建立···························································361引言·······························································································

6、············362实验材料与方法·······················································································363结果···········································································································394讨论··········································································

7、·································39第二部分蓝玉簪颗粒抑制慢性哮喘小鼠气道上皮下纤维化及TGF-β1表达······························································································411引言································