脑梗死患者糖耐量异常与颈动脉粥样硬化的关系

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1、天津医科大学硕士学位论文差异有统计学意义。IGT组与DM组相比，颈动脉MT增加，但差异无统计学意义。3．Logistic回归分析显示IGT组MT变化与TG、LDL-C、2h-pG、HbAIC、FBG有相关性。结论：动脉粥样硬化性脑梗死患者中存在相当部分的糖耐量异常脑梗死患者。在糖耐量异常脑梗死患者存在明显的颈动脉粥样硬化，IGT可能是早期促进动脉粥样硬化发生的重要危险因素。因此应当在既往未明确诊断DM病史的患者中常规开展OGTT检查，以早期发现IGT患者，积极进行生活指导和药物干预，弱化致动脉粥样硬化因素，减缓硬化斑块不稳定化进程，可降低动脉

2、粥样硬化性脑梗死患者的发生率，这将对脑梗死的防治有重要临床意义。关键词：糖耐量异常脑梗死动脉粥样硬化颈动脉内膜厚度糖尿病IIAbstractobjective：BycomparingbiochemicalindicatorsandcarotidatheroscieroticDlaqueofpatientswithcerebralinfarctionofthreegroups，toanalyzethepossibleeffectofimpairedglucosetoleranceonpatientswithcerebralinfarction．

3、Methods：InSeptember2011toSeptember2012，221patientswithcerebralinfarctioninourhospitaltreatmentwererecordedage，smoNng，drinking,hypertension，diabetes，etc．patientswiththefollowinghistorywereexcluded：malignanttumor,seriouslyabnormalliverandkidneyfunction，severelyabnormalcardiac

4、function，massiveproteinuria，oralcorticosteroids，acuteinflammation．Exclusioncriteria：patiemswithcerebralinfarctionwhowereafterthrombolyticther印y,patientswithcerebralinfarctionandatrialfibrillation，patientswithcerebralinfarctionwhowerenonarteryatherosclerosis(suchasvasculitis

5、orarteriovenousmalformation)．Byroutinebiochemicaltest，bloodfatseries(TG，TC，HDL—C!LDL．C)andbloodsugarseries(FBG、2h—pG、HbAlC)，bloodsugarin96patientswasnormal，and49patientswereimpairedglucosetolerance．patientswiththehistoryofdiabetesmellituswas76cases；patientswereperformedcerv

6、icalvascularultrasoundtodeterminethepresenceofplaqueornotincervicalartery．Torecordthelocationofplaqueandmeasuretherateoflumenstenosis．StatisticalmethodsSpSSl7．0statisticalsoftwarewasusedforprocessingdata．Thedatawasanalyzedusingsinglefactoranalysisofvariancefornumericalvaria

7、ble，chi—squaretestforratiobetweendifferentgroups．BinarylogisticregressionanalysiswasusedtotesttheassociationbetweenabnormalIMTandthefactorofproducingplaque．Results：1．221pmiems谢thcerebralinfarctionwerehospitalizedinourhospitalformSeptember2011toSeptember2012，ofwhich124casesw

8、erelargearteryatherosclerosis，anditaccountfor56．6％ofallpatientswithcerebralinfarct