内镜下治疗胃间质瘤的远期疗效研究-内科学（消化系病）专业毕业论文

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1、第三军医大学硕士学位论文Long-termOutcomesofEndoscopicResectionofGastricGISTsAbstractBackgroundand0bjective．．Gastrointestinalstromaltumors(GISTs)arethemostcommonsubmucosaltumorsofthegastrointestinaltract．Theyareconsideredtoariseanywhereinthewallofthedigestivetract，butespeciallycommoninthestomach(60—70％)．GISTshav

2、eavariablemalignancydegreerangingfrombenigntoaggressive，whosebiologicalcharacteristicsarenotyetclear．Sothesurgicalremovalofthelesionsisstillthemosteffectivemeansoftreatment．Inthepast，opensurgeryorlaparoscopicwedgeresectionwasofenchoosedtotreatgastricGISTswithoutmetastasis．Withtherapiddevelopmentinen

3、doscopictechnology，avarietyofendoscopictechniqueshavebeenappliedinthediagnosisandtreatmentforthem．Recently，therearemanyresearchesreportthatendoscopicsubmucosaldissection(ESD)andendoscopicful—thicknessresection(EFTR)aresuccessfullyusedtoresectgrasticGISTs，includingcompleteexcisionoflargeones．Ithasbee

4、nwidelyacceptedthatendoscopicresectionforgastricGISTsisfeasibleandsafeintheclinical．However,mostresearchesareaimedatdiscussingtheshort—termclinicalvaluesandcomplicationsofendoscopictreatments．Thelong—termeffectremainsunclear．Inthispaper,weretrospectivelyanalyzedtheclinicaldataof60patientswithgastric

5、GISTswhounderwentESDorEFTRfromApril2009toJanuary2014inourhospital．Theaimsofourstudyweretoassessthelong—termfeasibilityandsafetyofendoscopicresectionforgastricGISTswithnometastasis．Methods：Dataof60consecutivepatientswithgastricGISTswhounderwentendoscopicresectionfromApril2009toJanuary2014，werecollect

6、edintermsofthebasicinformation(IDnumber、name、gender、age)，clinicalpresentation，tumorsize，location，pathology,methodsandresultsofoperation，ect．Allpatientswerescheduledforregularfollow—up(1，6，and12monthspostoperativeandyearlythereafter)bygastroscopytoobservethehealing’万方数据第三军医大学硕士学位论文ofthewoundandrecurr

7、ence．Also，abdominalultrasonographywastakenyearlytoexcludemetastasis．Eachpatientwillbescheduledforregularfollow—upatleast1year,withanaveragefollow-upatleast2years，andthensummarizethelong-termoutcomesof