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1、甲茅软肝汤加减联合西药治疗肝硬化腹水的效果观察[摘要]目的探讨甲茅软肝汤加减联合西药治疗肝硬化腹水的临床效果。方法将186例肝硕化腹水患者随机分为治疗组94例,对照组92例。对照组采用护肝药物、抗病毒、抗感染、定期输注白蛋白、支持、利尿、腹腔排液等常规治疗;治疗组在对照组的基础上给予甲茅软肝汤加减治疗。治疗3个月后观察肝功能水平,评价临床疗效。结果治疗组肝功能改善情况明显优于对照组,差异冇统计学意义(P〈0・05);治疗组总冇效率为82.98%,明显优于对照组的63.04%,差异有统计学意义(P<0.05)。结论甲茅软肝汤加减联合西药能显著改善肝硬化腹
2、水患者的临床症状,明显改善肝功能指标,纠正并发症,疗效确切。[关键词]肝硬化腹水;甲茅软肝汤;屮西医结合治疗;效果观察[中图分类号]R575.2[文献标识码]A[文章编号]1674-4721(2014)09(c)-0129-03EffectobservationofmodifiedJiamaoRuangandecoctioncombinedwithwesternmedicineinthetreatmentofascitesduetocirrhosisYEXin-zhouDepartmentofHepatopathy,TraditionalChinese
3、MedicineHospitalofXiaochangCountyinHubeiProvince,Xiaochang432900,China[Abstract]ObjectiveToexploretheclinicaleffectofmodifiedJiamaoRuangandecoctioncombinedwithwesternmedicineinthetreatmentofascitesduetocirrhosis.MethodsOnehundredandeighty-sixpatientswithascitesduetocirrhosiswere
4、randomlydividedintotreatmentgroup(94cases)andcontrolgroup(92cases).Thecontrolgroupweregivenregulartreatmentincludingliverprotection,anti-virus,anti-infection,albumininfusionatregularintcrvals,supporting,dieresis,anddrainagofromabdominalcavity,thetreatmentgroupwasgivenJiamaoRuang
5、andecoctiononthebasisofcontrolgroup・After3monthstreatment,liverfunctionindexeswereobserved,andclinicaleffectwasevaluated.ResultsTheimprovementofliverfunctionindexesintreatmentgroupwasbetterthanthatincontrolgroup,withstatisticaldifference(P<0.05).Thetotalclinicaleffectiverateoftr
6、eatmentwas82.98%,significantlyhigherthanthatofcontrolgroup(63.04%),withstatisticaldifference(P<0.05).ConclusionModifiedJiamaoRuangandecoctioncombiningwithwesternmedicinecanremarkablyimprovetheclinicalmanifestationsinpatientswithascitesduetocirrhosisand1iverfunctionindexes,andcor
7、rectthecomplicationswithadefiniteeffect・[Keywords]Ascitesduetocirrhosis;JiamaoRuangandecoction;CombinedtreatmentoftraditionalChineseandwesternmedicine;Effectobservation肝硬化腹水是由于内分泌紊乱或血浆白蛋白减少导致血浆胶体渗透压降低而引起。大量腹水时腹内压增高,可引起呼吸怵I难甚至发绡,亦可诱发反流性食管炎而出现灼心及胸骨后不适或疼痛等症状,病变逐渐进展,可出现肝功能衰竭、门静脉高压和多
8、种并发症,死亡率高[1]。临床上多数肝硬化腹水患者都是由慢性乙型肝炎逐步发展而來,乙型肝炎病毒