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1、漠隐亭联合克罗米芬治疗无排卵型高泌乳素血症疗效观察李晓环(四川省宜宾市第一人民医院妇科四川宜宾644000)【摘要】目的：探讨漠隐亭联合克罗米芬治疗无排卵型高泌乳素血症的临床疗效。方法：回顾分析木院门诊就诊的己明确诊断并经澳隐亭治疗6月的仍无排卵型高泌乳素血症51例，根据治疗方案不同，随机分成澳隐亭组(n=26),单用漠隐亭1.25-2.5mg/d维持。联合用药组(n=25)澳隐亭1.25-2.5mg/d维持治疗，于月经的3・5天加用克罗米芬50-100mg/d口服，连用5天。两组疗程均为6月。
2、结果：澳隐亭维持治疗组月经量少R周期不规律者□例，月经量及周期正常者15例，无排卵14例，有排卵12例。联合用药组，月经量少且周期不规律者4例，月经量及周期正常者21例，无排卵者3例，有排卵者22例。结论：对无排卵型高泌乳素血症患者，单用澳隐亭，可降低血PRL水平，但月经恢复情况及排卵不理想，联合克罗米芬对恢复正常月经及排卵疗效较好。【关键词】高泌乳素血症；澳隐亭；克罗米芬；治疗【中图分类号1R588.6【文献标识码]A【文章编号11004-6194(2015)01-0068-02Bromocr
3、iptinecombinedwithclomipheneintreatmentofanovulatoryhyperprolactinemiaClinicalObservationLiXiaohuiDepartmentofGynecology,TheFirstPeople'sHospitalofYibinCity,SichuanProvince644000【Abstract]Objective：Toinvestigatebromocriptinecombinedwithclomipheneintr
4、eatmentofhyperprolactinemiaanovulatoryclinicalefficacy.Methods：Retrospectiveanalysisof51casesofpatientswithhyperprolactinemiainout・patientdepartmentofgynecologyweretreatedbybromocriptinefor6months,dependingonthetreatmentplanwererandomlydividedintothe
5、bromocriptinegroup(n二26),singlebromocriptine1.25-2.5mg/dtomaintain;Thecombinedtreatmentgroup(n=25),bromocriptine1.25・2.5mg/dmaintenancetherapy,Inthethirdtofivedaysofthemenstrualcycleplusclomiphene50-100mg/dorallyfor5days.Weretreatedfor6months.Results
6、：bromocriptinegoup:menstrualvolumelessandirregularmenstrualcycleswere11cases,normalmenstrualvolumeandnormalcyclewere15cases;anovulationwere14cases,therewere12casesofovulation.Thecombinedtreatmentgroup,menstrualvolumelessandirregularmenstrualcycleswer
7、e4cases,normalmenstrualvolumeandnormalcyclewere21cases;anovulationwere3cases,therewere22casesofovulation.Conclusion：patientswithanovulatoryhyperprolactinemiaalonewereusedbromocriptine,canreducelevelsofserumPRL,butrecoveryofmenstruationandovulationisn
8、otgood,combinedwithclomipheneresumenormalmenstruationandovulationefficacy.[Keywords]hyperprolactinemia；bromocriptine；clomifene；therapy高催乳素血症(hyperprolactinemia,HPRL)是多种原因引起的下丘脑■垂体■卵巢轴失调所致的外周血清催乳素持续高于正常状态。15%的无排卵妇女同时合并HPRL[1]O催乳素水平升高对卵巢功能有直接影响，能干扰卵泡发育
