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1、三氧水溶液经尿道前列腺恒压定位灌注治疗慢性前列腺炎的临床研究山东省济宁市中医院(济宁272000)王均友相建峰柳青摘要目的研究三氧水经尿道前列腺恒压定位灌注治疗慢性前列腺炎(CP)的临床价值。方法将符合诊断标准的238例CP患者随机分为三氧组和对照组，各119例。三氧组使用前列腺恒压定位灌注装置(专利号03271223.5)进行前列腺灌注治疗，灌注液为自配三氧水溶液40mL,每周2次，3~6次为一疗程；对照组进行常规治疗。通过对比病人治疗前后NIH-CPSI评分、症状评分及EPS常规镜检结果来观察临床价值。结果三氧组总有效率100%,对
2、照组总有效率73%,三氧组治愈、显效、总有效率均高于对照组(P<0.05)o结论在前列腺恒压定位灌注治疗前列腺炎的基础上，应用自制三氧水溶液作为灌注液治疗CP,其临床疗效优于对照组，能迅速改善症状，适用于各类CP,且长期应用无耐药之虞，无毒副作用。关键词慢性前列腺炎；三氧水；定位灌注ClinicalresearchonozonatedwatertransurethralprostateconstantpressurepositioningperfusionintreatmentofchronicprostatitisWangJunyou
3、,XiangJianfengDepartmentUrology,JiningtraditionalChineseMedicineHospitai,Jining272000,ChinaAbstractObjectiveToevaluatetheclinicalvalueoftransurethralprostateconstantpressurepositioningperfusionofozonatedwaterintreatmentofchronicprostatitis.Methods238patientsmetthediagnos
4、ticcriteriaofchronicprostatitiswererandomlydividedintotwogroups,treatmentgroupandcontrolgroup,with119casesineach.Ozonatedwater,42.5mg/L40ml,wasperfusedtoprosta/tewithconstantpositioningofprostateperfusiondevice(PatentNo.03271223.5).Inthetreatmentgroup,usagewas2timesperwe
5、ek,3-6timesforonecourse;thepatientsincontrolgroupwereofferedroutinedrugtreatment.Bycomparingpatients,beforeandaftertreatmentNIH-CPSIscore,symptomscoreandtheresultsofEPSresultsofconventionalmicroscopicobservation,toobservethechronicvalue.ResultsThetotaieffectiveratewere10
6、0%inthetreatmentgroup,and73%inthecontrolgroup,thecurativerate,obviouseffectiverateandtotalefficiencyrateofthetreatmentgroupwerehigherthanthoseofthecontrolgroup(P<0.05).ConclusionTheapplicationoftheappropriateconcentrationofozonedwaterasperfusionsolution,canrapidlyimprove
7、thesymptoms,andcanbeappliedtoalltypesofchronicprostatitis,withouttheriskofresistanceinthelong-1ermuse,alsonotoxicside.Keywordsozonatedwater;Chronicprostatitis;PositioningPerfusion慢性前列腺炎(chronicprostatitis,CP)发病率高达10%~50%⑴。目前前列腺炎的治疗方法多种多样，有药物治疗、前列腺按摩、生物反馈、热疗及中医治疗等，但常常疗效不佳
8、，而且复发率高。2009年12月我院设计了医用三氧水前列腺恒压定位灌注疗法治疗CP的新思路、新方法，并对238例CP病例进行了临床对比观察，经检索，国内外尚未有类似报道，现报告如下。资料与方法一、临床资料随
