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1、JLffl11崎IS98例够治»析2018-03-2110:12:00中国现代医生2018年2期朱加进伍万陈云龙[摘要]目的对川崎病(kawasakidisease,KD)患儿的临床表现及实验室结果进行分析,以提高诊治水平,减少并发症发生。方法收集2015年8月〜2017年7月收治的川崎病患儿98例,对临床资料进行整理和分析。结果研究发现本组患儿1〜3岁患病最多,共59例(A60.2%);临床表现屮发热最多见,占98.0%,U尨皲裂、杨梅舌占82.7%,颈部淋巴结肿大占74.5%,眼球结膜充血,占67.3%,皮疹占46.9%,手足硬肿及蜕皮占35.7%;可合并其他系统损伤,以支
2、气管肺炎最多见,共55例(56.1%):实验室检查:白细胞升高83例(84.7%),白细胞降低5例(5.1%);病程2周血小板增高93例(94.9%);C反应蛋白升高78例(79.6%);血沉增快66例(67.3%);血红蛋白<110g/L,32例(32.7%),血白蛋白降低18例(18.3%);冠状动脉扩张12例(12.2%)。结论儿童川崎病临床表现多样,应提髙认识,做到早期诊治,以减少并发症,降低病死率。[又键词]川崎病;儿:®.;临床表现;实验室检骑结果[巾阁分类号]R725.4[文献标I只码]B[文章编号】1673-9701(2018)02-0082-04[Abstra
3、ct]ObjectiveToanalyzetheclinicalmanifestationsandlaboratorytestresultsofchildrenwithKawasakidisease(KD)soastoimprovethediagnosisandtreatmentlevelandreducetheincidenceofcomplications.MethodsAtotalof98childrenwithKawasakidiseasewerecollectedfromAugust2015toJuly2017.Theclinicaldatawerecollected
4、andanalyzed.ResultsItwasfoundthatthechildrenaged1to3yearsaccountedforthemost,withatotalof59cases(60.2%).Inclinicalmanifestations,themostcommonwasfever,accountingfor98.0%,chappedlipsandbayberrytongueaccountedfor82.7%,hyperplasiaonneckaccountedfor74.5%,conjunctivalcongestionaccountedfor67.3%,s
5、kinrashesaccountedfor46.9%,andhandandfootsclerosisandmoltingaccountedfor35.7%.Othersystemdamagemaybecombinedwith,andbronchialpneumoniawasthemostcommon,withatotalof55cases(56.1%).LaboratoryExamination:whitebloodcellsin83cases(84.7%),leukopeniain5cases(5.1%),thrombocytosisat2weeksofcoursein93c
6、ases(94.9%),Creactiveproteinincreasedin78cases(79.6%),fasterESRin66cases(67.3%),hemoglobin<110g/Lin32cases(32.7%),decreasedserumalbuminin18cases(18.3%),andcoronaryarterydilatationin12cases(accountingfor12.2%).ConclusionKawasakidiseaseinchildrenhasvariousclinicalmanifestations,andtheawareness
7、toitshouldberaised.AndtheKawasakidiseaseshouldbediagnosedandtreatedtoreducecomplicationsandmortality.[Keywords]Kawasakidisease;Children;Clinicalmanifestations;Laboratorytestresults川崎病(Kawasakidisease,KD)乂稱皮肤黏膜淋巴结综合征(MCLS),是一种以全身血管炎性病变为病理特征的0身免疫性疾病,