肝脏疾病和肝脏手术与凝血机制的关系论文

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1、肝脏疾病和肝脏手术与凝血机制的关系论文【关键词】肝脏疾病；凝血功能；凝血4项指标肝脏是合成多种凝血因子的场所，并能合成和灭活纤维蛋白的溶解物与抗纤溶物质，在凝血、抗凝系统保持动态平衡中起重要调节作用。肝脏疾病与凝血机理有十分密切的关系，肝病时凝血指标常发生异常。严重时，临床上常有不同程度的出血现象。肝病患者至少表现有一项或几项凝血试验异常［１］。PT延长与肝病的损伤程度是正相关，肝损害时绝大部分患者有APTT延长［２］；肝病时如出现纤维蛋白明显减少，或有变性纤维蛋白原存在时，或因纤溶活力增加导致纤维蛋白降解产

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