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时间:2018-11-20
《升高咬合对青春期大鼠髁突软骨改建的影响论文》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、升高咬合对青春期大鼠髁突软骨改建的影响论文张红梅,丁寅,王欢,刘燕【关键词】髁突;牙合板;骨重建Influencesofocclusalverticalrisingoncondylarcartilageremodelinginadolescentrats【Abstract】AIM:Toinvestigatetheinfluencesofocclusalverticalrisingoncondylarcartilageremodelinginadolescentrats.METHODS:FortyfivealeSpragueDa
2、lydividedintoexperimentalgroup(n=20)andcontrolgroup(n=20).Animalsinexperimentalgroupolars.Theanimalsofexperimentalgroup,togetheratchedcontrols,e).Sectionsrightcondylesandstainedeasuredbyusingaputerassistedimageanalysissystem.RESULTS:Inparisonentalgroup;28daftertheap
3、plianceinsertion,thethicknessintheposteriorregionincreasedsignificantlyintheexperimentalgroup(P0.05).CONCLUSION:Theocclusalverticalrisingcouldleadtoadaptiveremodelingofcondylecartilageinadolescentrats.【Keyodeling【摘要】目的:探讨升高咬合对青春期大鼠髁突软骨改建的影响.方法:5周龄雄性SD大鼠40只,随机分为对照组和实
4、验组(双侧后牙牙合板升高咬合).实验组与对照组动物分别在7,14,21及28d时各取5只大鼠处死.取其右侧髁突作组织学HE染色观察.freelm,宽2.5mm,高1.0mm(第三磨牙).实验周期共28d,全部动物自由饮水,摄食.1.2方法戊巴比妥钠(40mg/kg)腹腔注射麻醉.采用自制头颅定位架固定大鼠头部,用Trophyx线牙片机在同一拍摄条件下摄片,观察实验组与对照组髁突在关节窝变化.于实验后7,14,21,28d各取大鼠5只,在深度麻醉下经心脏主动脉插管灌注0.1mol/L的PBS缓冲液(200mL/只)和40g/L多
5、聚甲醛(400mL/只),取出右侧颞下颌关节,40g/L多聚甲醛中固定24h,置150g/LEDTA中脱钙1,HE染色,光镜观察组织形态学变化.计算机PIXERAVieaK,etal.Alterationsoftherattemporomandibularjointinfunctionalposteriordisplacementofthemandible[J].AngleOrthod,2004,74(5):677-683.[3]DelatteM,VondenHoffJaryandsecondarycartilagesofth
6、eneonatalrat:Thefemoralheadandthemandibularcondyle[J].EurJOralSci,2004,112(2):156-162.[4]ContiPC,Santos,Kogaentofpainfultemporomandibularjointclickingizedclinicaltrial[J].JAmDentAssoc,2006,137(8):1108-1114.[5]鲍向红,陈金武,王美青,等.第一前磨牙缺失对髁突软骨影响的组织计量学[J].第四军医大学学报,2003,24(9)
7、:848-850.
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