无抽搐电休克（mect）合并利培酮、碳酸锂治疗双相躁狂临床对照研究

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1、无抽搐电休克（MECT）合并利培酮、碳酸锂治疗双相躁狂临床对照研宄吴亚涛张溪李玉梅赵仁珍熊娅芹（大理州第二人民医院云南大理671000）【摘要】R的：探讨无抽搐电休克（MECT）合并利培酮、碳酸锂与单纯药物治疗双相躁狂在起效时间、疗效及住院天数、治疗费用方面的差异。方法：将60例双相躁狂患者随机分为研究组30例和对照组30例，分别予MECT合并利培酮、碳酸锂治疗及单纯利培酮、碳酸锂治疗。疗效评定依据简明精神病评定量表（BPRS）、贝克躁狂量表（BRMS）评分。结果：研究组和对照组治疗前BPRS和BRMS评分差异无显著性（P均〉0.05）;两组BRMS评分于治疗后2、3周差异有显著

2、性（P<0.01）；两组不同时点分别与治疗前比较，均有显著性差异（P〈0.01）。研究组平均住院35.0天，对照组平均住院50.2天，两组比较有显著性差异（P<0.01）;研究组平均治疗费7500.90元，对照组平均治疗费1200.30元，两组比较有显著性差异（P<0.01）。结论：研宂组较对照组治疗双相躁狂患考疗效好，起效快，减少了住院天数和住院费用。【关键词】无抽搐电休克治疗；利培酮、碳酸锂治疗；双相躁狂【中图分类号】R97【文献标识码】A【文章编号】2095-1752（2016）06-0094-02ClinicalControlStudyonMECTCombinedwith

3、RisperidoneLithiumcarbonateTherapyinBipolarmaniaWuYatao,ZhangXi,LIYumei,etal.TheSecondPeople'sHospitalofDaliState,Dali671000,Yunnan,China【Abstract】ObjectiveTocomparethedifferencesintheinitialactiontime,theeffecthospitaltreatmentdaysandthetreatmentexpenseonbipolardisorderbetweenmodifiedelectro

4、convulsivetherapycombinedwithRisperidoneLithiumcarbonatemedicationanddrugtherapy.MethodsTotally60casesofbipolarmaniapatientswererandomlydividedintotwogroups.Therewere30casesinsdudygroup,theyreceivedtreatmentsofMECTcombinedwithRisperidoneLithiumcarbonate.But30caseswitchwereincontrolgroupreceiv

5、edRisperidoneLithiumcarbonateonly.TheeffectwasassessedaccordingtothescoresoftheBriefpsychiatricRatingScale(BPRS)andBech-RafaelsenManiaRatingScale(BRMS).ResultsSdudygrouptherap-Yandcontrolgrouptherapy,thescoresofBPRSandBRMShadnodifferencebeforetreatment(P>0.05),butsignificantdifferenceswere

6、foundafter23weeksoftreatment(P<0.01);significantdifferenceswerefoundofthetwogroupsscoresofBPRSandBRMSatdifferenttimescomparedwiththosebeforetreatment(P<0.01).Theaveragehospitaldaysofsdudygroupwere32.0daysandthoseofcontrolgroupwere50.2days,thedifferencewassignificant(P<0.01).Theaveragetreatmen

7、texpenseofsdudygroupwas7500.90yuanandthatofcontrolgroupwas12000.30yuan,thedifferencewassignificant(P<0.01).ConclusionMECTCombinedwithRisperidoneLithiumcarbonateTherapyisaeffectivefastsafeandeconomicalmethodintreatmentofBipolarmania.【Keywords】