榄香烯注射液在子宫切口妊娠介入治疗中的应用

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1、揽香烯注射液在子宫切口妊娠介入治疗中的应用上海中医药大学附属曙光医院200021【摘要】目的：探讨榄香烯注射液经子宫动脉灌注结合动脉栓塞，治疗切口妊娠的临床价值。方法：14例切U妊娠住院患者，入院1-3天内行双侧子宫动脉灌注栓塞介入治疗。随机分为榄香烯组7例，经子宫动脉灌注榄香烯20-40ml;甲氨蝶呤组7例，经子宫动脉灌注甲氨蝶呤50-100mg;双侧子宫动脉以明胶海绵粉/碎粒、明胶海绵条栓塞。结果：介入术后两组患者均未岀现子宫破裂大岀血。术后3天内观察血HCG变化。榄香烯组HCG下降〉50%6例，

2、＜50%1例；甲氨蝶呤组HCG下降〉50%4例，＜50%3例。结论：榄香烯区域灌注结合子宫动脉栓塞治疗切U妊娠疗效确切，榄香烯是中药莪术的提取物，有行气破血抗早孕的功效。可能在抑制胚胎细胞繁殖的同时，还促进局部血栓的形成，促使孕囊缺血、坏死。【关键词】子宫切U妊娠，榄香烯，区域灌注，动脉栓塞TheapplicationofElemeneinjectionintheinterventionaltreatmentforuterineincisionalpregnancyShanghaiShuguangho

3、spitalaffiliatedwithShanghaiUniversityofT.C.M.200021DepartmentofradiologyGenJian,YaoMing-rong，HuangXue-jing,LuMeng-ying，ZhangAn-junAbstract：Objective：Todiscusstheclinicalvalueofintra-arterialElemeneinjectioninfusion，combinedwitharterialembolization.Meth

4、od：Atotalof14patientswithuterineincisionalpregnancy，whoreceivedintra-arterialinfusioncombinedwitharterialembolizationwithin1雜3daysofadmission,werestudied.Theywererandomlyassignedintotwogroups：patientsingroupElemene(n=7)receivedintra-arterialinfusionofEl

5、emeneinjection(20-40ml).PatientsingroupMethotrexate(MTX，n=7)receivedintra-arterialinfusionofMethotrexate(50-100mg).Bilateraluterinearterialembolizationwasperformedwithgelfoamparticlesorgelfoamsponge.Result：Neithergroupexperiencedruptureofuterusaftertrea

6、tment.ThechangeofB-HCGwasobservedwithin3daysofoperation.AmongtheElemenegroup，6patientsexhibitedadecreaseinHCG>50%，and1exhibitedadecrease<50%；amongtheMTXgroup4patientsexhibitedadecrease>50%，and3exhibitedadecrease<50%.Conclusion：Themethodofint

7、ra-arterialElemeneinjectioninfusioncombinedwitharterialembolizationinincisionalpregnancyiseffective.ElemeneisanextractofRhizomaZedoariae.IthasaneffectofacceleratingQlandbloodcirculationwhichcouldpromotetheterminationofearlypregnancy.Itmayinhibittherepro

8、ductionofembryoniccell，whileencouragingtheformationofthrombosis，causingischemicnecrosisinthegestationalsac.Keywords：Incisionalpregnancy，elemene，intra-arterialinfusion,arterialembolization子宫切u妊娠是一种比较少见的异位妊娠，如果处理不当，会造成子宫破裂、大出血而危及生命