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1、亚高原地区PCT检测对细菌与病毒感染鉴别诊断的临床应用(1.丙宁市第三人民医院质控科青海丙宁810005）；(2.丙宁市第三人民医院医务科青海丙宁810005）；(3.青海省第三人民医院检验科青海丙宁810000）；(4.丙宁市第三人民医院质控科青海丙宁810005）【摘要】目的：探讨亚高原丙宁地IX降钙素原(PCT)定量检测在鉴别诊断细菌和病毒感染中的临床应用价值。方法：釆用定量固相免疫法测定收治我院176例患者的PCT浓度，其中87例细菌感染患者、89例病毒感染患者和40例正常体检者作为木组研究对象，
2、分别检测各组的血清降钙素原浓度水平及比较各组的阳性率。结果：细菌感染组、病毒感染组和正常体检组的PCT水平分布存在统计学差异(P<0.01);细菌感染组显著高于病毒感染组和正常体检组(P<0.01)；细菌性感染组阳性率达92.7%,明显高于病毒感染组阳性率10.9%,差异有极其显著性(P<0.01)。结论：PCT检测对于细菌性感染是一个敏感的新指标,而在病毒感染的患者中，PCT结果始终处于比较低的浓度水平，可为亚高原丙宁地区临床鉴别诊断细菌与病毒感染，及时合理使用抗生素提供依据。【关键词
3、】降钙素原(PCT);细菌感染；病毒感染【中图分类号】R512.6+4【文献标识码】B【文章编号】1003-5028(2015)7-0232-02TheClinicalApplicationofPCTTestinDiscriminatingandDiagnosingBacterialandVirusInfectionsinSub-PlateauRegionWangFanglZhangXiaoting2LiXiangwu3GaoLijunl(l.DeptofQualityInspection,The3rdX
4、iningPeople’sHospital,Xining,China810005)(2.DeptofMedicalAdministration,The3rdXiningPeople’sHospital,Xining,China810005）(3.DeptofClinicalLaboratory,The3rdXiningPeople’sHospital,Xining,China810005.)(CorrespondingAuthor:LuXiuzhenE-mail:575
5、501327@QQ.com【Abstract】Objective：ToexploreintotheclinicalvalueofPCTquantitativemeasurementindiscriminatingthebacterialandvirusinfectionsinsub-plateauXiningarea.Method：Quantitativesolid-phaseimmunoassayisadoptedfortestingthePCTconcentrationof176inpatients.
6、87bacterialinfectedinpatients,89virusinfectedinpatientsand40normalcaseswererespectivelyregardedasexperimentalobjects,andrespectivelyexaminetheirconcentrationlevelofserumPCTofeachgroupandcomparetheirpositiverate.Result:Thestatisticaldifference(P<0.01)of
7、PCTlevelhasappearedinthese3groups;thepositiverateofbacterialinfectedgroupis92.7%,obviouslyhigherthan10.9%ofvirusinfectedgroup,showsasharpdifference(P<0.01).Conclusion:PCTtestisanewandsensitiveindexforbacterialinfection.Amongtheinfectiousinpatients,PCTc
8、oncentrationlevelisalwaysremaininglow,providingthebasisforclinicaldiscriminationofbacterialandvirusinfectionsandrationaluseofantibioticsfortreatmentinsub-plateauXiningarea.【Keywords】PCT;Bacterialinfection;Virusinfec
