内源性眼内炎的研究进展

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1、内源性眼内炎的研宄进展摘要：内源性眼内炎是指细菌、真菌、病毒、寄生虫通过血液循环进入眼内引起感染性炎症。致病菌可来自远处的感染病灶或败血症。主要易感因素为静脉导管滞留、长期全身抗生素应用、中性粒细胞减少症、免疫抑制、AIDS、糖尿病、器官移植以及毒品等。按致病菌主要分为细菌性和真菌性两类，超过半数为真实验室检查中的（1，3）-D葡聚糖实验和PCR及多重PCR技术已越来越受到重视关键词：眼内炎内源性；易感因素；致病菌;实验室检查ResearchProgressofEndogenousEndophthalmitisGUOJing-yi

2、ng(DepartmentofOphthalmology,TianjinPublicSecurityHospital，Tianjin300000，China)Abstract：EndogenousEndophthalmitisreferstoinfectiousendophthalmitiscausedbybacteria、fungi、virusesorparasitesorcontaminatedbloodcirculationintointraoculararea.Pathogensarefromsepticemiaandfa

3、rwardinfectionfoci.Riskfactorsincludevenouscatheter实验室检查ResearchProgressofEndogenousEndophthalmitisGUOJing-ying(DepartmentofOphthalmology,TianjinPublicSecurityHospital，Tianjin300000，China)Abstract：EndogenousEndophthalmitisreferstoinfectiousendophthalmitiscausedbybacte

4、ria、fungi、virusesorparasitesorcontaminatedbloodcirculationintointraoculararea.Pathogensarefromsepticemiaandfarwardinfectionfoci.Riskfactorsincludevenouscatheter实验室检查ResearchProgressofEndogenousEndophthalmitisGUOJing-ying(DepartmentofOphthalmology,TianjinPublicSecurity

5、Hospital，Tianjin300000，China)Abstract：EndogenousEndophthalmitisreferstoinfectiousendophthalmitiscausedbybacteria、fungi、virusesorparasitesorcontaminatedbloodcirculationintointraoculararea.Pathogensarefromsepticemiaandfarwardinfectionfoci.Riskfactorsincludevenouscathete

6、rretention,long-termantibioticuse,neutropenia，immunosuppression，AIDS，diabetes,organtransplantandnarcoticdrugs.EndogenousEndophthalmitisinpathogensareprimarilyclassifiedinto2categories-oneisbacteriaandtheotherisfungi，whichhascausedmorethanhalfofthecases.Laboratoryexami

7、nationsof（1，3）-Ddextranexperiment，PCRandmultiplePCRtechnologyhavebeenpaidmoreandmoreattention.Keywords：Endophthalmitis；Endogenous；Infectious；Riskfactors；Pathogenicagent；Routinelabtest眼内炎是细菌、真菌、病毒、寄生虫、眼内自身抗原引起免疫反应等引起的眼内化脓性炎症。绝大多数为感染性眼内炎。依照致病微生物的来源可分为外源性眼内炎和内源性眼内炎两大类［1-

8、5］。内源性的占极少数，又叫转移性的眼内炎，是由于身体其他感染灶中的病源微生物（如：细菌、真菌、病毒、寄生虫等。其中病毒和寄生虫临床很少见。）随血循环播散入眼并在眼内繁殖引起感染。近几年来，该病在流行病学和易感因素、致病菌、实验室检查等领域的研究中