探讨温阳养心复律汤治疗阵发性房颤的疗效及对阵发性房颤患者血清超敏c-反应蛋白和血清.

《探讨温阳养心复律汤治疗阵发性房颤的疗效及对阵发性房颤患者血清超敏c-反应蛋白和血清.》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、探讨温阳养心复律汤治疗阵发性房颤的疗效及对阵发性房颤患者血清超敏C-反应蛋白和血清假性血友病因子水平的影响刘爱琴王庆云a雪［摘耍］目的：观察温阳养心复律汤对阵发性房颤患者血清超敏C-反应蛋白(High-sensitivityC-reactiveprotein,hs-CRP)水平及血清假性血友病因子(VascularVonWillebrandfactor,vWF)水平的影响，探讨温阳养心复律汤治疗阵发性房颤的作用机制及其有效性、安全性，促进临床应用。方法：选取2009年1/3-2012年1月于我院住院的阵发性房颤患者178例，随机分为2组：试验组(温阳养心复律汤组)97例，对照组

2、(胺碘酮组)81例。在治疗原发病及抗凝治疗基础上，对照组给予胺碘酮治疗，试验组给予温阳养心复律汤治疗，疗程4周。分别于治疗后1周、2周、3周及4周检测两组患者的血清hs-CRP及vWF浓度，并观察两组患者治疗后的复律情况、临床症状改善情况及不良反应发生情况。结果：hs-CRP及vWF浓度比较：治疗1周后、2周后、3周后、4周后试验组和对照组的hs-CRP及vWF浓度治疗前均下降，治疗前后比较，差异有统计学意义(P<0.05),而试验组较对照组下降更显著(P<0.05)o两组患者治疗4周后复律情况比较:试验组转复窦性心律者71例，有效率73.20%,对照组59例，有效

3、率为72.84%，两组比较差异无统计学意义(P>0.05)o［关键词］温阳养心复律汤胺碘酮房颤阵发性hs-CRPvWF临床症状TheEfficacyofWenYangYangXinFuLvDecoctioninPatientswithParoxysmalAtrialFibrillationandItsInfluenceonTheirSerumHigh-sensitivityC-reactiveProteinandSerumvonWillebrandFactorLiuAiqin,WangQingyun,LvXueAbstract:ObjectiveToObservethei

4、nfluenceofWenYangYangXinFuLvTangonserumhigh-sensitivityC-reactiveproteinandserumvonWillebrandfactorlevelsandinvestigateitsactionmechanism,effectiveness,andsafetyincuringpatientswithparoxysmalatrialfibrillation.Methods:178casesofparoxysmalatrialfibrillationpatientsattheauthor’shospitalf

5、romJanuary2009toJanuary2012weredivideinto2groups:97casesintestgroup(WenYangYangXinFuLvTanggroup)and81casesincontrolgroup(Amiodaronegroup).Basedonthetreatmentofprimarydiseaseandanticoagulanttherapy,thecontrolgroupacceptedAmiodaronetherapywhilethetestgroupacceptedWenYangYangXinFuLvTangtherapy.

6、Allthecasesaccept4weeksoftreatment.Theserumsh-CRPandvWFlevelsinpatientsafteroneweek,twoweeks,threeweeksandfourweeksofthetreatmentwerestudied.Thecardioversionimprovementofclinicalsymptoms,andadverseeventsofthetwogroupsofpatientsaftertreatmentwerealsorecorded.Results1.Comparethehs-CRPandvWFcon

7、centration：hs-CRPandvWFconcentrationofboththetestandthecontrolgroupdroppedoneweek,twoweeks,threeweeksandfourweeksafterthetreatment,whichhasstatisticallysignificant(P<0.05),whilethetestgroupdecreasedmoresignificantlythaninthecontrolgroup(P<0.0