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1、术前化疗联合手术治疗晚期大肠癌30例的临床研究云南省大理州人民医院普外科云南大理671000【摘要】目的：观察术前化疗联合手术治疗晚期大肠癌患者的效果。方法：选取2013年5月到2015年5月我院收治的晚期大肠癌患者作为研究对象，共计收集60例，将其根据患者的意愿(是否接受术前化疗)分为2组，一组为观察组(30例)，另一组为对照组(30例察组晚期大肠癌患者实施术前化疗联合手术治疗，对照组晚期大肠癌患者不实施术前化疗，对比两组患者术后的切U感染情况、愈合情况、发生吻合口瘘情况等。结果：观察组晚期大肠癌患者术后发生切口感染的概率为3.33%(1/30)，愈合概率为96.67%(29/3
2、0)，发牛.吻合口瘘的概率为6.67%(2/30)，对照组晚期大肠癌患者的切U感染概率、愈合概率、发生吻合U瘘概率分别为6.67%(2/30)、93.33%(28/30)、3.33%(1/30),由此得出，两组晚期大肠癌患者对比各项指标差异不明显(P〉0.05)。结论：只要在术前做好严格的准备工作，采取术前化疗联合手术治疗的方案不会对晚期大肠癌患者的治疗效果造成较大的影响。【关键词】术前；化疗；手术；晚期大肠癌Preoperativechemotherapycombinedwithsurgeryinthetreatmentof30casesofadvancedcolorectalc
3、ancerChenHongchunDepartmentofgeneralsurgery,DaliPeople'sHospitalofYunnanProvince,DaliYunnan671000,.【AbstractObjective】Toobservetheeffectofpreoperativechemotherapycombinedwithsurgeryinthetreatmentofpatientswithadvancedcolorectalcancer.Methods:atotalof2013mayto2015mayinourhospitalinpatientswitha
4、dvancedcolorectalcancerastheobjectofstudy,atotalofcollected60cases,thepatientswill(whethertoacceptthepreoperativechemotherapyaccordingtothedividedintotwogroups,agroupfortheobservationgroup(30cases),anothergroupascontrolgroup(30casesofobservationgroupinpatientswithadvancedcolorectalcancerpreope
5、rativechemotherapycombinedwithsurgeryinthetreatmentof,thecontrolgroupinpatientswithadvancedcolorectalcancerwithoutpreoperativechemotherapy,comparedtwogroupsofpatientswithpostoperativeincisioninfection,healing,anastomoticfistula.Results:observationgroupadvancedcolorectalcancerpatientsafterincis
6、ioninfectionprobabilityis3.33%(1/30),healingratewas96.67%(29/30),withanastomoticfistulaprobabilitywas6.67%(2/30),controlgroupinpatientswithadvancedcolorectalcancerincisioninfectionprobability,probabilityofhealing,occurrencekissanastomoticleakageprobabilitywas6.67%(2/30),93.33%(28/30),3.33%(1/3
7、0)respectively,thus,twosetsofadvancedcolorectalcancerpatientswithcomparingtheindexdifferenceisnotobvious(P>0.05).Conclusion:thepreoperativechemotherapycombinedwithsurgicaltreatmentwillnotaffectthetreatmentofpatientswithadvancedcolore
