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时间:2018-10-26
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1、多发性硬化症36例临床分析作者:雷建明,黎朝茂,江先娣,廖耿【摘要】目的:探讨多发性硬化的临床特点。方法:从临床、神经生理学、影像学等对MS病例进行回顾性分析。结果:36例MS中,男10例,女26例,发病年龄6~67岁,多见于青壮年女性,%病例是急性或亚急性发病,复发~缓解型占51%,病变部位中大脑半球19例,小脑5例,脑干5例脊髓21例,视神经12例,其中视神经脊髓炎占%。结论:MS起病急,病程短,脊髓、视神经、大脑易受侵犯,小脑、脑干相对少受累,临床症状多样化,以视力障碍、肢体无力较为突出,致残率较高,MRI对除视神经外的MS病灶有高度敏
2、感性,并可显示无临床症状的亚临床病灶。急性、亚急性期应用糖皮质激素疗效显著。【关键词】多发性硬化;临床分析;磁共振成像ClinicalAnalysison36CasesMu11ipleSclerosisAbstract:Objective:Toanalysetheclinicalcharacteristicsofmultiplesclerosis(MS).Method:Thecharacteristicsof36MScaseswereretrospectivelystudiedonclinic,neurophysiologyandimagin
3、g.Result:Among36MScases,lOinmaleand26infemale.ThefirstonsetagewasfSmainlyconsistedofrom6to67yearsold.Myoungandmiddle-age多发性硬化症36例临床分析作者:雷建明,黎朝茂,江先娣,廖耿【摘要】目的:探讨多发性硬化的临床特点。方法:从临床、神经生理学、影像学等对MS病例进行回顾性分析。结果:36例MS中,男10例,女26例,发病年龄6~67岁,多见于青壮年女性,%病例是急性或亚急性发病,复发~缓解型占51%,病变部位中大脑半球19
4、例,小脑5例,脑干5例脊髓21例,视神经12例,其中视神经脊髓炎占%。结论:MS起病急,病程短,脊髓、视神经、大脑易受侵犯,小脑、脑干相对少受累,临床症状多样化,以视力障碍、肢体无力较为突出,致残率较高,MRI对除视神经外的MS病灶有高度敏感性,并可显示无临床症状的亚临床病灶。急性、亚急性期应用糖皮质激素疗效显著。【关键词】多发性硬化;临床分析;磁共振成像ClinicalAnalysison36CasesMu11ipleSclerosisAbstract:Objective:Toanalysetheclinicalcharacteristic
5、sofmultiplesclerosis(MS).Method:Thecharacteristicsof36MScaseswereretrospectivelystudiedonclinic,neurophysiologyandimaging.Result:Among36MScases,lOinmaleand26infemale.ThefirstonsetagewasfSmainlyconsistedofrom6to67yearsold.Myoungandmiddle-agedwomen.%hadacuteandsubacuteonsetan
6、d5l%hadrelapses.Nineteencaseshadlesionsincerebralhemisphere,5casesincerebellum,5casesinbrainstem,2leasesinspinalcord,andl2casesinopticnerve.Thediagnosisof%patientswasDevicdisease.Conelusion:TheonsetofMSisurgent,andthecourseisshort.Spinalcord,opticnerveandeerebrumareeasytobe
7、invaded,butcerebellumandbrainstemarerelativelyseldomtobeinvolved.Clinicalsymptomsarevarious,buteyesightdamageandweaknessareprominent,whichcausethehighdisabilityrate.MRIishighlysensitivetolesionsexceptopticnerve,anditcanshowsubclinicallesions.TreatmentofacuteandsubacuteMSwit
8、hcorticosteroidsiseffective.Keywords:Multiplesclerosis;Clinicalanalysis;Magneticre
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