资源描述：
《莫沙必利与金双歧联合治疗慢性传输型便秘的临床研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、莫沙必利与金双歧联合治疗慢性传输型便秘的临床研究王民权(青海省果洛藏族自治州人民医院814000)【摘要】目的研宄探讨莫沙必利与金双歧联合治疗慢性传输型便秘的临床疗效，总结其临床用药经验与应用价值。方法选取我院2010年6月至2012年6月慢性传输型便秘的患者98例，按照数字表随机抽取法分成2组，各49例，观察组采取莫沙必利与金双歧联合治疗，对照组单纯使用莫沙必利治疗，观察对比两组临床疗效、不良反应及临床症状消退的时间。结果观察组治疗14d后疗效总有效率为93.9%(46/49),药物不良反应为2例，对照组治疗14d疗效总有效率为79.6%(39/49),药物不良反应为6例，两组疗效与不良
2、反应发生率对比均有显著差异(PC0.05);观察组临床症状消退时间要比对照组显著缩短(P<0.05)。结论莫沙必利与金双歧联合治疗慢性传输型便秘的临床疗效得到肯定，不仅可以提高临床疗效，迅速地缓解便秘相关症状，还能逐步重建与恢复正常的胃肠道功能，缩短疗效以避免单纯莫沙必利长期使用的副反应，安全可靠，值得推广。【关键词】莫沙必利金双歧慢性传输型便秘不良反应【中图分类号】R453【文献标识码】A【文章编号】2095-1752(2013)21-0112-02ClinicalstudyofmosaprideandGoldenBifidinthetreatmentofchronictransmiss
3、ionconstipation【Abstract】Objective:TostudytheclinicaleffectofmosaprideandGoldenBifidinthetreatmentofchronictransmissionconstipation,tosummarizetheclinicalexperienceandapplicationvalue.Methods:102patientsinourhospitalfrom2010Juneto2012June,thetransmissionofchronicconstipation,accordingtorandomlyext
4、ractionweredividedinto2groups,each51cases,theobservationgrouptakingmosaprideandGoldenBifidcombinedtreatment,thecontrolgroupweretreatedwithMosapride,comparisonoftwoclinicalefficacy,adversereactionandclinicalsymptomssubsidedtime.Results:Thecurativeeffectofgroup14daftertreatmentthetotaleffectiveratew
5、as93.9%(46/49),2casesofadversedrugreaction,controlefficacyoftreatmentgrouptotaleffectiverateof14dwas79.6%(39/49),6casesofadversedrugreactions,andtheadversereactionsofthetwogroupscurativeeffectcontrasttheincidencehadsignificantdifference(P<0.05);observationclinicalsymptomssubsidedsignificantlysh
6、orterthanthecontrolgroup(P<0.05).Conclusion:ThetherapeuticeffectofmosaprideandGoldenBifidinthetreatmentofchronictransmissionconstipationtobesure,notonlycanimprovetheclinicalefficacy,quicklyrelieveconstipationsymptoms,butalsograduallyreconstructionandrestorationofnormalgastrointestinalfunction,t
7、oavoidthesimplerelationshipwithcurativeeffectofMosapridesideeffects,long-termuseofsafeandreliable,worthyofpromotion.【keyword］mosaprideGoldenBifidtransmissionofchronicconstipationadversereaction慢性便秘(chronicconstip
