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ID:21046453
大小:68.17 KB
页数:5页
时间:2018-10-19
《胰岛素检测方法及其临床应用》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、摘要:目的:研究胰岛素的检测方法,分析对比研究结果意义,并探讨胰岛素检测的临床价值。方法:采用化学发光免疫分析法对294例2型糖尿病患者与同期健康者在空腹状态下进行胰岛素检测,其中217例2型糖尿病患者作为本次研宄的实验组,另外77例同期健康者作为对照组。同时对其进行胰岛素检测结果分析,根据检测结果来探讨胰岛素在临床上的应用价值。结果:在217例2型糖尿病患者中,血液胰岛素的测定结果为(60.7土17.5)mU/L,77例同期健康者对照组中,血液胰岛素的测定结果为(16.2土8.9)mU/L,差异有统计学意义(P关键词:胰岛素;检测方法;化学发光免疫分析法;糖尿病Abs
2、tract:Objective:Observetheeffectsofthalidomidetreatmentofelderlypatientsandrelapsedmultiplemyelomaclinicalefficacyandeffectivenessandsafety,andtoexplorethemosteffectivemechanismforthetreatmentofsenilerelapsedmultiplemyeloma.Method:clinicalobservationon13casesofprimarytreatmentand12patien
3、tsabove60yearsofagewithrecurrentelderlymyelomapatients,weremadeofarsenictrioxidecombinedwiththalidomidetreatment,intravenousarsenictrioxideforlOmg/dwhich,atthesametime,thecontinuousinjection28days,orallowdosethalidomide100200mmg/d,accordingtotheactualsituationofpatientsmaybeappropriateto
4、increase,themaximumthelimitis300mg/d,28daysforacourseoftreatment,takingtwocoursesoftreatment,efficacyandsideeffectswereobservedduringtheevaluationofcurativeeffect,inaccordancewiththestandardEBMTeffect,accordingtotheNCICTCAECTCAE(NationalCancerInstituteCommonTerminologyCriteriaforAdverseE
5、vents,version3)standardtoevaluatetheadversereaction.Result:inthe13patientsnewlydiagnosed5casesofpartialremission(38.46%),5casesofprogress(38.46%),and3casesineffective(23.08%).In12casesofsenilemultiplemyelomapatients,4casesofpartialremission(33.3%),5cases(41%)hadimprovement,3cases(25%)are
6、invalid,thetotaleffectiveratewas74.3%.Observedthat,inthetreatmentofcommonadversereactionsarenauseaandfatigue,abdominaldistensionandconstipation,skinrash,liverinjury,neutropenia,butaftertreatmentwillimprove.Conclusion:Arsenictrioxidethalidomideforthetreatmentofsenilerelapsedmultiplemyelom
7、aissafeandeffective,worthyofpromotion.Keywords:Arsenictrioxide;Thalidomide;Elderlyandrelapsedmultiplemyeloma胰岛素是机体内唯一具有降低血糖作用的激素,是由胰岛0细胞受外源性或内源性物质刺激分泌的蛋白质激素,胰岛素的分子量5700,由A、B两个肽链组成。胰岛素合成的速度受血浆葡萄糖浓度影响,当血糖的浓度升高时,胰岛3细胞中的胰岛素原含量增加,则胰岛素合成加速。胰岛素还是临床上治疗糖尿病的主要用药,故而胰岛素的测定具有一定的临床意义。化
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