宫颈高级别鳞状上皮内病变-cinⅲ术后病理危险因素分析

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1、授予单位代码10089学号或申请号20153428中国图书分类号R711.74HebeiMedicalUniversity硕士学位论文专业学位宫颈高级别鳞状上皮内病变-CINⅢ术后病理危险因素分析研究生：张雪姣导师：李利教授专业：妇产科学二级学院：第四医院2018年3月目录中文摘要···········································································································1英文摘要

2、··········································································································3英文缩写··········································································································5研究论文宫颈高级别鳞状上皮内病变-CINⅢ术后病理危险因素分析前言··

3、··········································································································6材料与方法·······························································································7结果···········································

4、······························································7附表·······································································································12讨论·················································································

5、························15结论··········································································································16参考文献·································································································17综述子宫颈癌发病的高危因素及

6、筛查······················································18致谢··················································································································29个人简历·········································································

7、································30中文摘要宫颈高级别鳞状上皮内病变-CINⅢ术后病理危险因素分析摘要目的：宫颈高级别鳞状上皮内病变(HSIL)是一种癌前病变，有发展为浸润癌的风险。本研究回顾总结术前病理结果明确诊断为宫颈高级别鳞状上皮内病变锥切术后的病理转归特点，为临床提供指导及借鉴。方法：1收集回顾2012年2月至2017年8月我院306例经阴道镜下宫颈组织活检病理证实为宫颈高级别鳞状上皮内病变(主要原病理分型CINⅢ)的患者。通过分析其相关的临床资料，分析宫颈高级

8、别鳞状上皮内病变锥切术后的病理转归及相关影响因素。2统计学分析采用SPSS22.0统计软件进行数据分析处理。用x2检验统计分析相关临床随访指标(患者年龄、就诊原因、TCT、HPV、妇科查体、妇科B超、肿瘤标志物、术中情况)与锥切术后病理的构成比关系。P<0.05差异有统计学意义。结果：1.306例宫颈高级别鳞状上皮内病变患者中有130例锥切术后病理结果回报为宫颈癌，发生率为42.48%。余176例病例锥切术后病理结果为良性病变或癌前病变。2.宫颈高级别鳞