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1、患者教育对舌下特异性免疫治疗的变应性鼻炎患者依从性的影响林碧玉黄少鹏陈勇李瑞玉(通讯作者)沈帆(福建省立医院耳鼻喉头颈外科福建福州350001)【摘要】目的研究患者教育对舌下特异性免疫治疗的变应性鼻炎患者依从性的影响。方法518例尘螨过敏且进行舌K特异性免疫治疗的变应性鼻炎患者分为试验组(200例)和对照组(318例)，在首诊、治疗后第1,3,8周对试验组患者进行电话随访和患者教育，而对照组患者仅门诊就医。治疗后第4,8周行两组间脱落情况统计和脱落原因分析。结果治疗4周后，试验组和对照组患者的脱落率分别为12.5%和37.
2、4%(P<0.01)。治疗8周后，试验组和对照组的脱落率分别是24.3%和53.7%(P<0.01)。两组脱落原因有显著差异性是患者对坚持长期用药缺乏信心和如何具体用药困惑。(P<0.01,P<0.05)；结论患者教育有助于降低接受舌下特异性免疫治疗患者的脱落率，提高患者的依从性。【关键词】患者教育变应性鼻炎脱落率脱落原因【屮图分类号】R471【文献标识码】A【文章编号】2095-1752(2014)08-0068-02InfluenceofPatientsEducationonComplianceofPatientswi
3、thAllergicRhinitistoSublingualImmunotherapyLinBiyuHuangShaopengChenYongLiRuiyuShenFan(DepartmentofOtorhinolaryngology，HeadandNeckSurgeryofFujianProvincialHospital,Fuzhou,Fujianprovince,350001)【Abstract】ObjectiveTostudytheinfluenceofpatientseducationoncomplianceofp
4、atientswithallergicrhinitistreatedwithsublingualimmunotherapy.Methods518allergicrhinitispatientshadrandomlyenrolledfromtheFujianprovincialhospitalanddividedintocontrol(318patients)andexperimentalgroup(200patients).Theexperimentalgrouphadacceptedpatienteducationpro
5、gramincludingon-siteeducation,follow-upbyphoneandeducationat1st,3rdand8thweekaftertreatment,whilethecontrolhadonlyacceptedinvestigationforreasonsofdrop-out.Duringthe8weeks,situationandreasonsofdrop-outinbothgroupsateachvisitwererecordedandanalyzed.ResultsDuringfir
6、st4weeks,12.5%patientsinexperimentalgroupand37.4%patientsincontrolgrouphadbeenfailedtoadheringwiththemedicalprescription,andthestatisticallysignificantdifferencehadbeenobserved(P<0.01).After8weeks,rateofdrop-outintheexperimentalgroupwas24.3%,butthecontrolwas53.7%,
7、andsignificantdifference(P<0.01)existedbetweengroups;Therateofdrop-outresultedfromlong-termtherapyorconfusionofimmunotherapyprocedurewereboth2.2%,butthecontrolwere21.5%and10.7%respectively,thedifferences(P<0.01，P<0.05)betweengroupswerestatisticallysignificanttoo;C
8、onclusionPatientseducationcouldsignificantlydecreasetherateofdrop-outandimprovethecomplianceduringsublingualimmunotherapy.【Keywords】PatienteducationAlle
