不同起源部位频发室早射频消融术对左心房结构及功能的影响

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1、授予单位代码10089学号或申请号20153124中国图书分类号R541.7HebeiMedicalUniversity硕士学位论文专业学位不同起源部位频发室早射频消融术对左心房结构及功能的影响研究生：赵彦蕾导师：谢瑞芹教授专业：内科学二级学院：河北医科大学第二医院2018年3月目录中文摘要················································································1英文摘要············································

2、····································3英文缩写··············································································5研究论文不同起源部位频发室早射频消融术对左心房结构及功能的影响前言··············································································6材料与方法······································

3、·······························6结果··············································································9附图··············································································15附表··············································································

4、20讨论··············································································27结论··············································································29参考文献········································································30综述室早诱发心肌病的研究进展·················

5、······························33致谢·····················································································42个人简历··············································································43中文摘要不同起源部位频发室早射频消融术对左心房结构及功能的影响摘要目的：通过对比不同起源部位频发室早射频消融术前及术后左心房结构及功能，了解

6、不同起源部位频发室早射频消融术对左心房的影响，以指导临床治疗。方法：收集2014年12月至2017年9月于我院住院，动态心电图示室早负荷>10000次/24h，且成功行射频消融术患者123例。依据术中定位室早来源分为右室流出道游离壁24例(年龄：43±18岁，男性：10例)，右室流出道间隔部36例(年龄：44±11岁，男性30例)，主动脉窦上36例(年龄：43±15岁，男性：26例)，主动脉窦下27例(年龄：47±12岁，男性：16例)。入选患者于术前、术后1天、术后2周、术后1月应用心脏超声二维斑点追踪技术观察左心房结构及功能指标。选取32例

7、既往体健，无烟酒等不良嗜好的成年人做为对照组。结果：LAD术前较对照组显著增大(P<0.05),术后2周较术前显著减小(P<0.05)，但未达到对照组水平。组间比较：术后2周以右室流出道间隔部来源改善显著，后依次为游离壁、主动脉窦上、主动脉窦下来源(P<0.05)。S%术前较对照组显著较低(P<0.05)，术后1月较术前显著改善(P<0.05)，但未达到对照组水平。组间比较：术后1月以右室流出道间隔部来源改善显著，后依次为游离壁、主动脉窦上、主动脉窦下来源(P<0.05)。A-VTI术前游离壁组较对照组无显著差异(P>0.05)，余三组较对照组

8、显著降低，术后2周均有逐渐改善趋势，但未达到统计学差异(P>0.05)。LAEF术前较对照组无显著差异(P>0.05)，LVEF术前较对照组显著减低(